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自然计划生育的流行病学研究。

Epidemiological studies of natural family planning.

作者信息

Gray R H, Kambic R T

机构信息

Department of Population Dynamics, Johns Hopkins University, School of Hygiene and Public Health, Baltimore MD 21205.

出版信息

Hum Reprod. 1988 Jul;3(5):693-8. doi: 10.1093/oxfordjournals.humrep.a136768.

Abstract

The prevalence of the use of natural family planning (NFP) can be estimated from sample surveys of married women in the reproductive ages (MWRA). Surveys in developed and developing countries during the past decade indicate that the prevalence of NFP use varies from 0 to 11%. In addition, if one considers NFP use in relation to other contraceptive methods, the percentage of all current contraceptors who use NFP varies from 1 to 35%. This suggests that NFP is an important method in certain countries. Pregnancy rates for NFP vary widely, but most reliable studies report 1-year life-table pregnancy rates between 10 and 25/100 woman-years. The Billings ovulation method consistently has higher pregnancy rates than the sympto-thermal method and NFP users generally have among the highest pregnancy rates compared to other methods. The major safety issue concerning NFP is the risk of adverse pregnancy outcomes associated with aged gametes. There are suggestions from a number of investigations that conceptions distant from ovulation have a higher risk of spontaneous abortion and a higher proportion of male births. The findings with respect to birth defects or multiple pregnancies are less consistent, although some studies have reported an increased risk of chromosomal anomalies.

摘要

自然计划生育(NFP)的使用 prevalence 可通过对育龄已婚妇女(MWRA)的抽样调查来估计。过去十年在发达国家和发展中国家进行的调查表明,NFP 的使用 prevalence 从 0% 到 11% 不等。此外,如果将 NFP 的使用与其他避孕方法相关联来看,所有当前使用避孕方法的人中使用 NFP 的比例从 1% 到 35% 不等。这表明 NFP 在某些国家是一种重要的方法。NFP 的妊娠率差异很大,但大多数可靠研究报告的 1 年生命表妊娠率在每 100 妇女年 10 至 25 例之间。比林斯排卵法的妊娠率始终高于症状体温法,与其他方法相比,NFP 用户的妊娠率通常也是最高的。与 NFP 相关的主要安全问题是与老化配子相关的不良妊娠结局风险。多项调查表明,排卵时间较远的受孕有更高的自然流产风险和更高比例的男婴出生。关于出生缺陷或多胎妊娠的研究结果不太一致,尽管一些研究报告染色体异常风险增加。

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