Division of Pulmonary Medicine, 2013Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Division of Pulmonary, Critical Care and Sleep Medicine Division, 232890Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.
J Intensive Care Med. 2021 Jan;36(1):80-88. doi: 10.1177/0885066619886816. Epub 2019 Nov 10.
There has been limited investigation into the procedural outcomes of patients undergoing emergent endotracheal intubation (EEI) by a critical care medicine (CCM) specialist outside the intensive care unit (ICU). We hypothesized that EEI outside an ICU would be associated with lower rates of first pass success (FPS) as compared to inside an ICU.
We performed a retrospective cohort study of all adult patients admitted to our academic medical center between January 1, 2016, and July 31, 2018, who underwent EEI by a CCM practitioner. The primary outcome of FPS was identified in the EEI procedure note. Secondary outcomes included difficult intubation (> 2 attempts at laryngoscopy) and mortality following EEI.
In total, 1958 patients (1035 [52.9%] inside ICU and 923 [47.1%]) outside an ICU) were included in the final cohort. Unadjusted rate of FPS was not different between patients intubated out of the ICU and patients intubated inside of the ICU (689 [74.7%] vs 775 [74.9%]; = .91). There was also no difference in FPS between groups after adjusting for predictors of difficult intubation and baseline covariates (odds ratio: 0.95; 95% confidence interval, 0.75-1.2, = .65). Mortality of patients undergoing EEI out of the ICU was higher at each examined time interval following EEI.
For EEI done by CCM practitioners, rate of FPS is not different between patients undergoing EEI outside an ICU as compared to inside an ICU. Despite the lack of difference between rates of procedural success, patient mortality following EEI outside an ICU is higher than EEI inside an ICU at all examined time points during hospitalization.
在重症监护病房(ICU)之外,由重症医学(CCM)专家进行紧急气管插管(EEI)的患者,其操作结果的研究还很有限。我们假设,与在 ICU 内进行相比,在 ICU 外进行 EEI 的首次尝试成功率(FPS)会更低。
我们对 2016 年 1 月 1 日至 2018 年 7 月 31 日期间在我们学术医疗中心住院的所有成年患者进行了回顾性队列研究,这些患者由 CCM 医生进行 EEI。EEI 操作记录中确定了 FPS 这一主要结果。次要结果包括 EEI 后困难插管(>2 次喉镜尝试)和死亡率。
共有 1958 名患者(1035 名在 ICU 内[52.9%]和 923 名在 ICU 外[47.1%])被纳入最终队列。在 ICU 外进行插管的患者与在 ICU 内进行插管的患者之间,未校正的 FPS 率无差异(689[74.7%] vs 775[74.9%]; =.91)。在调整困难插管的预测因素和基线协变量后,两组之间的 FPS 也没有差异(比值比:0.95;95%置信区间,0.75-1.2, =.65)。在 ICU 外进行 EEI 的患者在 EEI 后每个检查的时间间隔的死亡率都更高。
对于由 CCM 医生进行的 EEI,在 ICU 外进行 EEI 的患者与在 ICU 内进行 EEI 的患者之间,FPS 的成功率没有差异。尽管操作成功率没有差异,但在 ICU 外进行 EEI 的患者在住院期间所有检查时间点的死亡率都高于在 ICU 内进行 EEI 的患者。