Collaborative Innovation Center of Biomedical Functional Materials and Key Laboratory of Biofunctional Materials of Jiangsu Province, School of Chemistry and Materials Science , Nanjing Normal University , Nanjing 210023 , People's Republic of China.
Beijing National Laboratory for Condensed Matter Physics, Institute of Physics , Chinese Academy of Sciences , Beijing 100190 , People's Republic of China.
J Am Chem Soc. 2019 Dec 18;141(50):19533-19537. doi: 10.1021/jacs.9b09546. Epub 2019 Nov 14.
Quantitative morphological evolution is of great importance in nanochemistry. In this work, morphology of silver nanotriangles (AgNTs) is quantitatively evolved under the guidance of DNA. First, intact AgNTs are prepared relying on the protection of horseradish peroxidase. Then different regions of AgNTs are sequentially etched by C-rich DNA, leading to DNA-guided postshaping of AgNTs. In combination with atomically resolved images and theoretical simulation, a model is established to track the postshaping process. Since real-time morphological evolution of AgNTs is determined with spectra, a series of AgNTs with specific corners can be obtained by controlling incubation time. The DNA-guided postshaping is sequence and structure dual-dependent, and a mechanism is proposed based on metal-base interaction, surface energy of faces, and freedom of DNA structure. In addition, the postshaping is further used to design DNA-mediated biosensors. This study provides a precise and quantitative method of controlling morphology of anisotropic metallic nanomaterials.
定量形态演变在纳米化学中具有重要意义。在这项工作中，银纳米三角形（AgNTs）的形态在 DNA 的指导下进行了定量演变。首先，依靠辣根过氧化物酶的保护来制备完整的 AgNTs。然后，通过富含 C 的 DNA 依次蚀刻 AgNTs 的不同区域，从而导致 AgNTs 的 DNA 引导后成型。结合原子分辨图像和理论模拟，建立了一个模型来跟踪后成型过程。由于 AgNTs 的实时形态演变是通过光谱来确定的，因此通过控制孵育时间可以获得具有特定角的一系列 AgNTs。DNA 引导的后成型是序列和结构双重依赖的，并基于金属-碱基相互作用、面的表面能和 DNA 结构的自由度提出了一种机制。此外，后成型进一步用于设计 DNA 介导的生物传感器。这项研究为控制各向异性金属纳米材料的形态提供了一种精确和定量的方法。
