Department of Neurology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, Croatia.
Department of Neurosurgery, University Clinical Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
Clin Neurol Neurosurg. 2020 Jan;188:105586. doi: 10.1016/j.clineuro.2019.105586. Epub 2019 Nov 4.
Paroxismal non-kinesigenic dyskinesia (PNKD) is a rare movement disorder manifesting as choreatic/dystonic movements, usually lasting from minutes to up to 4 h, with perserved consciousness during attacks. Primary PNKD are idiopathic or genetic disorders while secondary PNKD are associated with various neurologic and medical conditions. We present a case with PNKD and right sided hemidystonia in association with celiac disease, responsive to gluten-free diet, not previously reported in available literature. In conclusion, diagnostic tests for celiac disease should be a part of etiological investigations in patients with otherwise unexplained movement disorders including PKND. Gluten free diet could produce a favorable clinical response in those patients.
阵发性非运动源性运动障碍（PNKD）是一种罕见的运动障碍，表现为舞蹈症/肌张力障碍运动，通常持续数分钟至 4 小时，发作时意识保持清醒。原发性 PNKD 为特发性或遗传性疾病，而继发性 PNKD 与各种神经和医学状况相关。我们报告了一例伴有 PNKD 和右侧半身肌张力障碍的乳糜泻病例，对无麸质饮食有反应，这在现有文献中尚无报道。总之，对于其他原因不明的运动障碍患者，包括 PKND，应将乳糜泻的诊断性检查作为病因学研究的一部分。无麸质饮食可能会使这些患者产生良好的临床反应。
