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[睾丸肿瘤的超声造影检查]

[Contrast-enhanced ultrasonography of testicular tumours].

作者信息

Lock G

机构信息

Klinik für Innere Medizin, Albertinen-Krankenhaus Hamburg, Süntelstr. 11a, 22457, Hamburg, Deutschland.

出版信息

Urologe A. 2019 Dec;58(12):1410-1417. doi: 10.1007/s00120-019-01065-z.

DOI:10.1007/s00120-019-01065-z
PMID:31712858
Abstract

Scrotal ultrasound with high-resolution transducers and additional display of vascularisation in colour-coded ultrasonography is the method of choice for the detection and characterisation of testicular tumors. Within the last decade, testicular ultrasonography has been further refined and improved by the possibilities of contrast-enhanced ultrasound (CEUS).CEUS may be especially helpful in the assessment of vascularisation disorders (e.g., incomplete torsion, segmental perfusion disorders, abscesses) or testicular foci remaining equivocal even after colour-coded ultrasonography.The basic idea in the application of CEUS in scrotal sonography is the possibility to differentiate between avascular, hypo- and hypervascular findings, with a lack of perfusion generally considered as a sign of benignity. Vice versa, detection of vascularisation speaks for neoplasia but not necessarily for malignity (e.g., Leydig cell tumors). CEUS is especially valuable in the correct classification of small (<1.5 cm) testicular foci.This review summarizes the present knowledge on indications, implications and limitations of the application of CEUS in testicular tumors.

摘要

使用高分辨率换能器的阴囊超声检查以及彩色编码超声检查中血管化的额外显示是检测和表征睾丸肿瘤的首选方法。在过去十年中,超声造影(CEUS)的应用使睾丸超声检查得到了进一步完善和改进。CEUS在评估血管化障碍(如不完全扭转、节段性灌注障碍、脓肿)或即使在彩色编码超声检查后仍不明确的睾丸病灶方面可能特别有用。在阴囊超声检查中应用CEUS的基本理念是能够区分无血管、低血管和高血管表现,一般认为缺乏灌注是良性的标志。反之,血管化的检测提示肿瘤形成,但不一定提示恶性(如睾丸间质细胞瘤)。CEUS在正确分类小(<1.5厘米)睾丸病灶方面特别有价值。本综述总结了目前关于CEUS在睾丸肿瘤应用中的适应证、意义和局限性的知识。

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2
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Contrast-enhanced ultrasound as a valuable imaging modality for characterizing testicular lesions.超声造影在睾丸病变特征成像中有重要价值。
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The Application Value of Contrast-Enhanced Ultrasound in Testicular Occupied Lesions.超声造影在睾丸占位性病变中的应用价值。
Comput Math Methods Med. 2021 Jun 11;2021:9962970. doi: 10.1155/2021/9962970. eCollection 2021.

本文引用的文献

1
Testicular epidermoid cysts: a reevaluation.睾丸表皮样囊肿:再评价。
BMC Urol. 2019 Jun 11;19(1):52. doi: 10.1186/s12894-019-0477-1.
2
Diagnostic performance of contrast-enhanced ultrasound (CEUS) in testicular pathologies: Single-center results.对比增强超声(CEUS)在睾丸病变中的诊断性能:单中心结果。
Clin Hemorheol Microcirc. 2019;73(2):347-357. doi: 10.3233/CH-190579.
3
The EFSUMB Guidelines and Recommendations for the Clinical Practice of Contrast-Enhanced Ultrasound (CEUS) in Non-Hepatic Applications: Update 2017 (Short Version).
EFSUMB 指南与共识——临床应用中超声造影(CEUS)的操作规范:非肝脏超声造影 2017 年更新版(简短版)
Ultraschall Med. 2018 Apr;39(2):154-180. doi: 10.1055/s-0044-101254. Epub 2018 Mar 6.
4
Diagnostic accuracy and interobserver agreement of contrast-enhanced ultrasound in the evaluation of residual lesions after treatment for malignant lymphoma and testicular cancer: a retrospective pilot study in 52 patients.对比增强超声在恶性淋巴瘤和睾丸癌治疗后残留病灶评估中的诊断准确性和观察者间一致性:52 例患者的回顾性试点研究。
Leuk Lymphoma. 2018 Nov;59(11):2622-2627. doi: 10.1080/10428194.2018.1439170. Epub 2018 Feb 27.
5
Value of Multiparametric US in the Assessment of Intratesticular Lesions.多参数超声在睾丸内病变评估中的价值。
Radiology. 2017 Nov;285(2):640-649. doi: 10.1148/radiol.2017161373. Epub 2017 Jun 16.
6
Straight Vessel Pattern and Rapid Filling Time: Characteristic Findings on Contrast-Enhanced Sonography of Testicular Lymphoma.直血管模式与快速充盈时间:睾丸淋巴瘤超声造影的特征性表现
J Ultrasound Med. 2016 Jul;35(7):1593-9. doi: 10.7863/ultra.15.05049. Epub 2016 Jun 22.
7
Real-Time Elastography and Contrast-Enhanced Ultrasonography in the Evaluation of Testicular Masses: A Comparative Prospective Study.实时弹性成像与超声造影在睾丸肿块评估中的应用:一项对比性前瞻性研究
Ultrasound Med Biol. 2016 Aug;42(8):1807-15. doi: 10.1016/j.ultrasmedbio.2016.03.026. Epub 2016 May 13.
8
Multiparametric Sonography of Testicular Hematomas: Features on Grayscale, Color Doppler, and Contrast-Enhanced Sonography and Strain Elastography.睾丸血肿的多参数超声检查:灰阶、彩色多普勒、超声造影及应变弹性成像特征
J Ultrasound Med. 2015 Jul;34(7):1319-28. doi: 10.7863/ultra.34.7.1319.
9
Growing indications for CEUS: The kidney, testis, lymph nodes, thyroid, prostate, and small bowel.超声造影(CEUS)的应用指征不断增加:肾脏、睾丸、淋巴结、甲状腺、前列腺和小肠。
Eur J Radiol. 2015 Sep;84(9):1675-84. doi: 10.1016/j.ejrad.2015.05.008. Epub 2015 May 14.
10
CEUS Time Intensity Curves in the Differentiation Between Leydig Cell Carcinoma and Seminoma: A Multicenter Study.对比性增强超声时间强度曲线在鉴别睾丸间质细胞瘤和精原细胞瘤中的应用:一项多中心研究
Ultraschall Med. 2016 Apr;37(2):201-5. doi: 10.1055/s-0034-1398841. Epub 2015 Jan 21.