Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, People's Republic of China.
Mikrochim Acta. 2019 Nov 12;186(12):769. doi: 10.1007/s00604-019-3909-4.
A combination between an ionic liquid and melamine-formaldehyde aerogel on the carbon fibers was developed for in-tube solid-phase microextraction of estrogens with high efficiency. The sorbent has a high enrichment capability for several estrogens. Scanning electron microscopy showed that the aerogel on the carbon fibers has a porous three-dimensional network structure. Several important parameters such as sampling volume, sampling rate, the concentration of organic solvent in sample, pH value of sample as well as desorption time were optimized towards estrogen targets. Comparing with melamine-formaldehyde aerogel coating, the coating gave higher extraction efficiency. Comparing with melamine-formaldehyde aerogel coating, the new coating displays higher extraction efficiency. An online analytical method of estrogens was established, by the combination between in-tube solid-phase microextraction and high performance liquid chromatography with diode array detector. Analytical figures of merit include low limits of detection (<0.20 μg L), wide linearity (0.15-20 μg L), high enrichment factors (1028-1256), good extraction repeatability (RSDs<2.5%) and satisfactory preparation repeatability (RSDs<10.5%). The method was applied to the determination of trace estrogen targets in plastic bottle, tap water and surface water. Graphical abstractSchematic representation of online combination between in-tube solid-phase microextraction and high performance liquid chromatography, based on an ionic liquid (IL)-modified melamine-formaldehyde (MF) aerogel coating on carbon fibers (CFs) in a polyether-etherketone (PEEK) tube.
一种基于离子液体和三聚氰胺-甲醛气凝胶的组合被开发用于高效的管内固相微萃取雌激素。该吸附剂对几种雌激素具有高富集能力。扫描电子显微镜显示，碳纤维上的气凝胶具有多孔的三维网络结构。对采样体积、采样速率、样品中有机溶剂的浓度、样品的 pH 值以及解吸时间等几个重要参数进行了优化，以针对雌激素目标物。与三聚氰胺-甲醛气凝胶涂层相比，该涂层具有更高的萃取效率。与三聚氰胺-甲醛气凝胶涂层相比，新涂层显示出更高的萃取效率。通过管内固相微萃取和高效液相色谱与二极管阵列检测器的结合，建立了雌激素的在线分析方法。分析的优点包括低检测限（<0.20μg L）、宽线性范围（0.15-20μg L）、高富集因子（1028-1256）、良好的萃取重复性（RSDs<2.5%）和令人满意的制备重复性（RSDs<10.5%）。该方法应用于塑料瓶、自来水和地表水痕量雌激素目标物的测定。
