Department of Ophthalmology, Ophtalmopôle, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris, AP-HP, Université Paris 5, Sorbonne Paris Cité, Paris, France.
Centre de Recherche des Cordeliers, INSERM U1138, Team 17, Université Paris Descartes Sorbonne Paris Cité, Paris, France.
Ocul Immunol Inflamm. 2021 Feb 17;29(2):346-351. doi: 10.1080/09273948.2019.1681472. Epub 2019 Nov 12.
: To assess the choroidal vascularity index (CVI) in birdshot chorioretinopathy (BSCR) patients.: The CVI was calculated as the ratio of luminar area to the total subfoveal choroidal area on enhanced-depth imaging optical coherence tomography. Intraocular inflammation was defined by the presence of macular edema and/or vitritis and/or vasculitis and/or papillitis.: Eighty BSCR patients and 22 healthy controls were included. Foveal choroidal thickness was lower in the BSCR compared with the control group ( < 0.001). CVI was not different between the two groups. CVI was significantly higher in BSCR patients with inflammatory activity ( = 0.004). Using a multivariate linear regression model, longer disease duration was associated with lower CVI ( = 0.038), whereas the presence of papillitis was associated with a higher CVI ( = 0.003).: The CVI was not different between the BSCR and the control group. However, the CVI may be used as a new tool for monitoring inflammatory activity in BSCR.
: 评估鸟枪弹样脉络膜视网膜病变（BSCR）患者的脉络膜血管指数（CVI）：CVI 是通过增强深度成像光学相干断层扫描计算得出的，即脉络膜下毛细血管总面积与脉络膜下毛细血管总面积的比值。眼内炎症通过黄斑水肿和/或睫状体炎和/或血管炎和/或视乳头炎来定义。: 共纳入 80 例 BSCR 患者和 22 名健康对照者。BSCR 组的中心凹脉络膜厚度低于对照组（<0.001）。两组间 CVI 无差异。在有炎症活动的 BSCR 患者中，CVI 显著更高（=0.004）。使用多元线性回归模型，疾病持续时间较长与 CVI 较低相关（=0.038），而视乳头炎的存在与 CVI 较高相关（=0.003）。: CVI 在 BSCR 组和对照组之间无差异。然而，CVI 可能被用作监测 BSCR 炎症活动的新工具。
