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Bempedoic Acid for Lowering LDL Cholesterol.

作者信息

Honigberg Michael C, Natarajan Pradeep

机构信息

Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

出版信息

JAMA. 2019 Nov 12;322(18):1769-1771. doi: 10.1001/jama.2019.16598.

DOI:10.1001/jama.2019.16598
PMID:31714973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6865332/
Abstract
摘要

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本文引用的文献

1
Effect of Bempedoic Acid vs Placebo Added to Maximally Tolerated Statins on Low-Density Lipoprotein Cholesterol in Patients at High Risk for Cardiovascular Disease: The CLEAR Wisdom Randomized Clinical Trial.贝匹地酸对比安慰剂联合最大耐受他汀类药物治疗对心血管疾病高危患者的低密度脂蛋白胆固醇的影响：CLEAR Wisdom 随机临床试验。
JAMA. 2019 Nov 12;322(18):1780-1788. doi: 10.1001/jama.2019.16585.
2
Very High-Risk ASCVD and Eligibility for Nonstatin Therapies Based on the 2018 AHA/ACC Cholesterol Guidelines.基于2018年美国心脏协会/美国心脏病学会胆固醇指南的极高风险动脉粥样硬化性心血管疾病及非他汀类疗法的适用情况
J Am Coll Cardiol. 2019 Aug 6;74(5):712-714. doi: 10.1016/j.jacc.2019.05.051.
3
Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy.贝特帕酸联合依折麦布固定剂量复方制剂在最大耐受他汀治疗的高胆固醇血症和高 CVD 风险患者中的应用。
Eur J Prev Cardiol. 2020 Apr;27(6):593-603. doi: 10.1177/2047487319864671. Epub 2019 Jul 29.
4
Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance.贝匹地酸治疗高胆固醇血症及他汀类药物不耐受患者的疗效和安全性。
J Am Heart Assoc. 2019 Apr 2;8(7):e011662. doi: 10.1161/JAHA.118.011662.
5
Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol.贝匹地酸降低 LDL 胆固醇的安全性和有效性。
N Engl J Med. 2019 Mar 14;380(11):1022-1032. doi: 10.1056/NEJMoa1803917.
6
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.2018年美国心脏协会/美国心脏病学会/美国心血管和肺康复协会/美国医师助理学会/美国心脏协会/美国预防医学学会/美国糖尿病协会/美国老年医学会/美国药剂师协会/美国临床内分泌医师协会/美国国家脂质协会/美国初级保健医师学会血胆固醇管理指南：执行摘要：美国心脏病学会/美国心脏协会临床实践指南工作组报告
J Am Coll Cardiol. 2019 Jun 25;73(24):3168-3209. doi: 10.1016/j.jacc.2018.11.002. Epub 2018 Nov 10.
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N Engl J Med. 2019 Jan 3;380(1):11-22. doi: 10.1056/NEJMoa1812792. Epub 2018 Nov 10.
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Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome.依洛尤单抗与急性冠脉综合征后的心血管结局。
N Engl J Med. 2018 Nov 29;379(22):2097-2107. doi: 10.1056/NEJMoa1801174. Epub 2018 Nov 7.
9
Statin-Associated Myopathy-An Elusive Clinical Problem.他汀类药物相关肌病——一个难以捉摸的临床问题。
JAMA Intern Med. 2018 Sep 1;178(9):1230. doi: 10.1001/jamainternmed.2018.3128.
10
Efficacy and safety of bempedoic acid added to ezetimibe in statin-intolerant patients with hypercholesterolemia: A randomized, placebo-controlled study.在不能耐受他汀类药物的高胆固醇血症患者中，添加苯扎贝特酸与依折麦布联合治疗的疗效和安全性：一项随机、安慰剂对照研究。
Atherosclerosis. 2018 Oct;277:195-203. doi: 10.1016/j.atherosclerosis.2018.06.002. Epub 2018 Jun 12.