Bristol Centre for Surgical Research, University of Bristol, Bristol, UK
North Bristol NHS Trust, Bristol, UK.
BMJ Open. 2019 Nov 11;9(11):e030817. doi: 10.1136/bmjopen-2019-030817.
The effect of mode of anaesthesia in emergency surgery is uncertain. This scoping review will identify and summarise the evidence for local, regional or general anaesthetic in adult patients undergoing emergency surgical procedures.
Scoping review methodology will be followed. The search will be run in EMBASE and Medline. Further articles will be identified from searching references in relevant studies. A descriptive analysis will be performed considering the following main outcomes; mortality, length of stay, intensive care unit (ICU) admission, postoperative pain and morbidity. Data on complications including acute coronary syndrome, stroke, thromboembolic events, delirium, acute kidney injury, respiratory tract infection, surgical site infection and study-specific additional outcomes will also be collected.
No ethics approval is required. The results will be used to inform a funding application for a clinical trial comparing local/regional anaesthetic with general anaesthetic. The study will be disseminated via peer-reviewed manuscript and conferences.
Results will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Statement. There are currently no registries that accept scoping reviews.
麻醉方式对急诊手术的影响尚不确定。本范围性综述旨在确定并总结全身麻醉、局部或区域麻醉对接受急诊手术的成年患者的影响。
本综述将采用范围性综述方法。检索将在 EMBASE 和 Medline 中进行。将从相关研究的参考文献中搜索进一步的文章。将考虑以下主要结局进行描述性分析：死亡率、住院时间、重症监护病房（ICU）入住率、术后疼痛和发病率。还将收集包括急性冠状动脉综合征、中风、血栓栓塞事件、谵妄、急性肾损伤、呼吸道感染、手术部位感染和研究特异性其他结局等并发症的数据。
本研究无需伦理批准。研究结果将用于为一项比较局部/区域麻醉与全身麻醉的临床试验提供资金申请。该研究将通过同行评审的论文和会议进行传播。
结果将根据系统评价和荟萃分析扩展的首选报告项目（PRISMA-ScR）声明进行报告。目前尚无接受范围性综述的注册处。
