Kesteloot H, van de Werf F, Marchandise B, Sluyts R
Acta Cardiol. 1979;34(5):301-9.
Moxaprindine, a new anti-arrhythmic drug, with characteristics similar to aprindine, has been demonstrated to be highly effective in suppressing ventricular arrhythmias occurring before, during and after maximal exercise stress testing. This effect was obtained both in subjects with clinically normal hearts and in a limited number of patients with ischemic heart disease. These findings demonstrate the efficacy and safety of anti-arrhythmic treatment by drugs prolonging ventricular depolarization for ventricular arrhythmias occurring during exercise.
莫沙丙胺,一种新型抗心律失常药物,其特性与安搏律定相似,已被证明在抑制最大运动应激试验前、试验期间及试验后的室性心律失常方面非常有效。在临床心脏正常的受试者以及少数缺血性心脏病患者中均获得了这一效果。这些发现证明了通过延长心室去极化的药物进行抗心律失常治疗对运动期间发生的室性心律失常的有效性和安全性。