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一例重叠综合征(硬皮病和多发性肌炎)合并心肌损伤导致突发胸痛。

A case of overlap syndrome (scleroderma and polymyositis) associated with the development of sudden chest pain due to myocardial damage.

作者信息

Kaneko Akira, Kajihara Ikko, Miyashita Azusa, Ihn Hironobu

机构信息

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

出版信息

Drug Discov Ther. 2019;13(5):297-298. doi: 10.5582/ddt.2019.01072.

Abstract

Myocardial injury with systemic sclerosis (SSc) causes pericarditis and arrhythmia, and polymyositis-induced muscle inflammation causes myocarditis. We report a rare case of overlap syndrome (SSc and polymyositis) who presented with sudden chest pain secondary to myocardial fibrosis. Although the etiology of chest symptoms in collagen disease was difficult to identify, cardiac magnetic resonance imaging (MRI) revealed not myocarditis but myocardial fibrosis in our case. Synthetic judgement of serum brain natriuretic peptide/ troponin T levels and cardiac MRI is useful in the search for the cause of chest symptoms even in patients with collagen diseases.

摘要

系统性硬化症(SSc)所致的心肌损伤会引起心包炎和心律失常,而多发性肌炎所致的肌肉炎症会引起心肌炎。我们报告了1例重叠综合征(SSc和多发性肌炎)的罕见病例,该患者因心肌纤维化出现突发胸痛。尽管胶原病患者胸部症状的病因难以明确,但在我们的病例中,心脏磁共振成像(MRI)显示并非心肌炎,而是心肌纤维化。即使对于胶原病患者,综合判断血清脑钠肽/肌钙蛋白T水平及心脏MRI对于寻找胸部症状的病因也很有用。

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