青少年期有患严重精神疾病风险人群的睡眠障碍。
Sleep disturbances in youth at-risk for serious mental illness.
机构信息
Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada.
Centre for Youth Bipolar Disorder, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
出版信息
Early Interv Psychiatry. 2020 Jun;14(3):373-378. doi: 10.1111/eip.12898. Epub 2019 Nov 13.
AIM
To investigate sleep behaviours of youth at-risk for serious mental illness (SMI).
METHODS
This study included 243 youth, ages 12 to 25:42 healthy controls, 41 asymptomatic youth at-risk for mental illness (stage 0); 53 help-seeking youth experiencing distress (stage 1a) and 107 youth with attenuated syndromes (stage 1b). The Pittsburgh Sleep Quality Index was used to assess sleep dysfunction.
RESULTS
Stage 1b individuals indicated the greatest deficit in global sleep dysfunction (F = 26.18, P < .0001). Stages 1a and 1b reported significantly worse subjective sleep quality, a longer sleep latency, increased use of sleep medications as well as greater daytime dysfunction compared to the asymptomatic groups.
CONCLUSION
Research investigating sleep behaviours of youth considered to be at-risk for SMI is limited. This study provides early evidence that sleep disturbances are worse for individuals considered to be at higher risk of illness development.
目的
调查有患严重精神疾病（SMI）风险的青年的睡眠行为。
方法
本研究纳入了 243 名年龄在 12 至 25 岁之间的青年：42 名健康对照者，41 名无症状的有精神疾病风险的青年（阶段 0）；53 名正在经历痛苦的寻求帮助的青年（阶段 1a）和 107 名有轻度综合征的青年（阶段 1b）。使用匹兹堡睡眠质量指数评估睡眠障碍。
结果
阶段 1b 个体的整体睡眠功能障碍最为严重（F=26.18，P<.0001）。与无症状组相比，阶段 1a 和 1b 报告的主观睡眠质量更差、睡眠潜伏期更长、使用睡眠药物的频率更高以及白天功能障碍更大。
结论
针对被认为有患 SMI 风险的青年的睡眠行为研究有限。本研究提供了早期证据，表明对于被认为患病风险更高的个体，睡眠障碍更为严重。
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