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基于数据挖掘的方法研究摄入含咖啡因咖啡对稳态视觉诱发电位信号产生的影响。

Data mining based approach to study the effect of consumption of caffeinated coffee on the generation of the steady-state visual evoked potential signals.

机构信息

Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, 769008, India.

TCS Research and Innovation, Kolkata, 700156, India.

出版信息

Comput Biol Med. 2019 Dec;115:103526. doi: 10.1016/j.compbiomed.2019.103526. Epub 2019 Oct 31.

Abstract

The steady-state visual evoked potentials (SSVEP), are elicited at the parieto-occipital region of the cortex when a light source (3.5-75 Hz), flickering at a constant frequency, stimulates the retinal cells. In the last few decades, researchers have reported that caffeine enhances the vigilance and the executive control of visual attention. However, no study has investigated the effect of caffeinated coffee on the SSVEP response, which is used for controlling the brain-computer interface (BCI) devices for rehabilitative applications. The current work proposes a data mining-based approach to gain insight into the alterations in the SSVEP signals after the consumption of caffeinated coffee. Recurrence quantification analysis (RQA) of the electroencephalogram (EEG) signals was employed for this purpose. The EEG signals were acquired at seven frequencies of photic stimuli. The stimuli frequencies were chosen such that they were distributed throughout the EEG frequency bands. The prominent SSVEP signals were identified using the Canonical Correlation Analysis (CCA) method. Several statistical features were extracted from the recurrence plot of the SSVEP signals. Statistical analyses using the t-test and decision tree-based methods helped to select the most relevant features, which were then classified using Automated Neural Network (ANN). The relevant features could be classified with a maximum accuracy of 97%. This supports our hypothesis that the consumption of caffeinated coffee can alter the SSVEP response. In conclusion, utmost care should be taken in selecting the features for designing BCI devices.

摘要

稳态视觉诱发电位(SSVEP)是当光刺激(3.5-75 Hz)以恒定频率闪烁刺激视网膜细胞时,在大脑顶枕部皮层产生的。在过去的几十年中,研究人员已经报告称,咖啡因可以增强警觉性和视觉注意力的执行控制。然而,目前还没有研究调查含咖啡因咖啡对 SSVEP 反应的影响,SSVEP 反应用于控制用于康复应用的脑机接口(BCI)设备。当前的工作提出了一种基于数据挖掘的方法,以深入了解摄入含咖啡因咖啡后 SSVEP 信号的变化。为此,采用了脑电信号的递归定量分析(RQA)。在七个光刺激频率下采集 EEG 信号。选择这些刺激频率是为了使它们分布在整个 EEG 频带中。使用典型相关分析(CCA)方法识别突出的 SSVEP 信号。从 SSVEP 信号的递归图中提取了几个统计特征。使用 t 检验和基于决策树的方法进行的统计分析有助于选择最相关的特征,然后使用自动神经网络(ANN)对其进行分类。相关特征的分类准确率最高可达 97%。这支持了我们的假设,即摄入含咖啡因的咖啡会改变 SSVEP 反应。总之,在设计 BCI 设备时,应格外注意选择特征。

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