Rehabilitation Service, The Marqués de Valdecilla University Hospital, Valdecilla Avenue s/n. C.P.: 39008 Santander, Cantabria, Spain.
Faculty of Nursing, University of Cantabria, Valdecilla Avenue s/n., 39008 Santander, Cantabria, Spain.
Int J Environ Res Public Health. 2019 Nov 15;16(22):4513. doi: 10.3390/ijerph16224513.
Cerebral palsy is one of the main causes of disability in childhood. Resistance therapy shows benefits in increasing strength and gait in these patients, but its impact on motor function is not yet clear. The objective was to analyze the impact of resistance therapy on the improvement in the motor function using a review and meta-analysis. A comprehensive literature research was conducted in Medline (PubMed), Institute for Scientific Information (ISI) Web of Knowledge, and Physiotherapy Evidence Database (PEDro) in relation to clinical trials in which resistance therapy was used and motor function was assessed. Twelve controlled clinical trials and three non-controlled clinical trials (only one intervention arm) studies were identified. In terms of pre-post difference, the overall intra-group effect was in favor of resistance therapy intervention: standardized mean difference (SMD) = 0.37, 95% confidence interval (CI) = 0.21 to 0.52, < 0.001 (random-effects model), with moderate heterogeneity ( = 59.82%). SMDs were also positive by restricting to each of the analyzed scales: SMD = 0.37, 1.33, 0.10, and 0.36 for Gross Motor Function Measure (GMFM), Lateral Step Up (LSU), Time Up and Go (TUG), and Mobility Questionnaire (MobQue) scales, respectively. Regarding the difference between groups, the results showed a high heterogeneity ( < 99%), with the mean difference (MD) also favorable for the GMFM scale: MD = 1.73, 95% CI = 0.81 to 2.64, < 0.001 (random-effects model). Our results support a positive impact of resistance therapy on motor function. Further studies should delve into the clinical relevance of these results.
脑性瘫痪是儿童残疾的主要原因之一。阻力疗法在增加这些患者的力量和步态方面显示出益处，但它对运动功能的影响尚不清楚。目的是通过综述和荟萃分析来分析阻力疗法对改善运动功能的影响。针对使用阻力疗法和评估运动功能的临床试验，在 Medline（PubMed）、科学信息研究所（ISI）Web of Knowledge 和物理治疗证据数据库（PEDro）中进行了全面的文献检索。确定了 12 项对照临床试验和 3 项非对照临床试验（仅 1 个干预组）研究。就前后差异而言，总体组内效应有利于阻力疗法干预：标准化均数差（SMD）=0.37，95%置信区间（CI）=0.21 至 0.52， < 0.001（随机效应模型），具有中度异质性（ =59.82%）。通过限制在分析的每个量表上进行分析，SMD 也是阳性的：SMD=0.37、1.33、0.10 和 0.36 分别用于总体运动功能测量量表（GMFM）、侧步上升量表（LSU）、起立-行走计时测试量表（TUG）和移动能力问卷量表（MobQue）。关于组间差异，结果显示高度异质性（ < 99%），GMFM 量表的平均差异（MD）也有利于阻力疗法：MD=1.73，95%CI=0.81 至 2.64， < 0.001（随机效应模型）。我们的结果支持阻力疗法对运动功能的积极影响。进一步的研究应该深入探讨这些结果的临床相关性。
Zotero 插件
