Division of Global Health Equity, Harvard Medical School, Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Clin Chest Med. 2019 Dec;40(4):857-869. doi: 10.1016/j.ccm.2019.07.010.
Traditional tuberculosis (TB) infection control focuses on the known patient with TB, usually on appropriate treatment. A refocused, intensified TB infection control approach is presented. Combined with active case finding and rapid molecular diagnostics, an approach called FAST is described as a convenient way to call attention to the untreated patient. Natural ventilation is the mainstay of air disinfection in much of the world. Germicidal ultraviolet technology is the most sustainable approach to air disinfection under resource-limited conditions. Testing and treatment of latent TB infection works to prevent reactivation but requires greater risk targeting in both low- and high-risk settings.
传统的结核病（TB）感染控制侧重于已知的结核病患者，通常侧重于适当的治疗。本文提出了一种重新聚焦、强化的结核病感染控制方法。结合主动病例发现和快速分子诊断，FAST 方法被描述为一种关注未治疗患者的简便方法。自然通风是世界上许多地区空气消毒的主要方法。在资源有限的情况下，杀菌紫外线技术是空气消毒最可持续的方法。检测和治疗潜伏性结核病感染可预防再激活，但在低风险和高风险环境中都需要更有针对性的风险定位。
