Suppr超能文献

在社区医院急诊室用丁丙诺啡治疗阿片类药物戒断:一项外展计划。

Treating Opioid Withdrawal With Buprenorphine in a Community Hospital Emergency Department: An Outreach Program.

机构信息

Department of Emergency Medicine, Arnot Ogden Medical Center, Elmira, NY.

Department of Emergency Medicine, Arnot Ogden Medical Center, Elmira, NY.

出版信息

Ann Emerg Med. 2020 Jan;75(1):49-56. doi: 10.1016/j.annemergmed.2019.08.420. Epub 2019 Nov 13.

Abstract

STUDY OBJECTIVE

We assess the feasibility of using our community hospital emergency department (ED) as an immediate portal to medication-assisted treatment for patients in opioid withdrawal.

METHODS

This was a prospective observational cohort study. In collaboration with an outpatient substance abuse treatment center, we alerted the public through media outlets that individuals could receive immediate buprenorphine treatment for opioid withdrawal in the ED, with rapid referral for medication-assisted treatment. If medication-assisted treatment intake was delayed, patients could return for up to 2 more days for buprenorphine administration to treat their withdrawal symptoms. We measured compliance with initial follow-up and continued treatment engagement at 30 and 90 days.

RESULTS

The study was conducted during 12 months. A total of 62 patients were enrolled, evaluated for buprenorphine criteria, and referred for medication-assisted treatment. Fifty subjects were compliant with their first medication-assisted treatment follow-up visit (81% [95% confidence interval 71% to 91%]), and 43 of these 50 patients were still engaged in medication-assisted treatment at 30 days (86% [95% confidence interval 76% to 96%]), with 33 of the 50 still engaged at 90 days (66% [95% confidence interval 53% to 79%]). We observed no instances of precipitated withdrawal or other adverse reactions in the ED.

CONCLUSION

A substantial number of patients responded to this program and received accelerated engagement in medication-assisted treatment. Such a program is feasible in the community hospital ED and may prevent some individuals from relapsing into high-risk illicit drug use when immediate medication-assisted treatment is not otherwise available.

摘要

研究目的

我们评估使用我们社区医院急诊部(ED)作为阿片类药物戒断患者接受药物辅助治疗的直接途径的可行性。

方法

这是一项前瞻性观察性队列研究。我们与一家门诊药物滥用治疗中心合作,通过媒体向公众发出警报,称个体可以在 ED 立即接受丁丙诺啡治疗阿片类药物戒断,随后迅速转介接受药物辅助治疗。如果药物辅助治疗延迟,患者可以在接下来的 2 天内返回 ED 接受丁丙诺啡治疗,以缓解戒断症状。我们测量了初始随访和 30 天和 90 天的持续治疗参与度。

结果

该研究进行了 12 个月。共有 62 名患者入组,评估丁丙诺啡标准,并转介接受药物辅助治疗。50 名患者符合首次药物辅助治疗随访要求(81%[95%置信区间 71%至 91%]),其中 43 名患者在 30 天内仍继续接受药物辅助治疗(86%[95%置信区间 76%至 96%]),50 名患者中有 33 名仍在 90 天内接受治疗(66%[95%置信区间 53%至 79%])。我们在 ED 未观察到戒断反应或其他不良反应。

结论

相当数量的患者对该计划做出了反应,并加快了药物辅助治疗的参与。这样的计划在社区医院 ED 是可行的,可以防止一些人在没有立即获得药物辅助治疗的情况下重新陷入高风险非法药物使用。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验