Department of Neurosurgery, Lariboisière Hospital, Paris VII-Diderot University, Paris, France; Department of Surgical Sciences, University of Torino, Torino, Italy.
Department of Neurosurgery, Lariboisière Hospital, Paris VII-Diderot University, Paris, France; Division of Neurosurgery, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
World Neurosurg. 2020 Feb;134:e771-e782. doi: 10.1016/j.wneu.2019.10.190. Epub 2019 Nov 14.
Surgical management of extensive skull base tumors, such as chordoma and chondrosarcoma, remains very challenging. The need for gross total removal to improve survival must be weighed against the risk of injury to neurovascular structures and the loss of stability at the craniovertebral junction. In cases of tumors that are already compromising craniovertebral junction stability, the occipital condyle can be exploited as a deep keyhole to reach the clivus, petrous apex, and sphenoid sinus.
We performed an anatomic study on 7 cadaveric specimens to describe the main landmarks and boundaries of the corridor. We also provide a clinical case to demonstrate the feasibility of the approach.
In all specimens, using the space provided by the condyle, it was possible to drill the petrous bone up to the posterior wall of the sphenoid sinus following the direction of the inferior petrosal sinus. To successfully complete the approach, after the hypoglossal canal was exposed, endoscopic assistance was needed to overcome the narrowing of the visual field provided by the microscope.
In cases of invasive skull base tumor involving the craniovertebral junction and affecting its stability, the occipital condyle can be exploited as a deep keyhole to the homolateral and contralateral petrous apex, clivus, and sphenoid sinus.
广泛颅底肿瘤(如脊索瘤和软骨肉瘤)的手术治疗仍然极具挑战性。为了提高生存率,必须进行大体全切除,但这必须权衡损伤神经血管结构和颅颈交界区不稳定的风险。对于已经影响颅颈交界区稳定性的肿瘤,枕骨髁可被利用作为深部锁孔来到达斜坡、岩骨尖和蝶窦。
我们对 7 具尸体标本进行了解剖学研究,以描述通道的主要标志和边界。我们还提供了一个临床病例,以证明该入路的可行性。
在所有标本中,利用髁突提供的空间,沿着下岩窦的方向,可以钻透岩骨到达蝶窦后壁。为了成功完成手术,暴露舌下神经管后,需要内镜辅助来克服显微镜提供的视野狭窄。
在颅颈交界区受累并影响其稳定性的侵袭性颅底肿瘤的情况下,枕骨髁可被利用作为同侧和对侧岩骨尖、斜坡和蝶窦的深部锁孔。