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早孕期与期待治疗对脊柱裂患者的管理——我们是否都在谈论一种风险分层方法?

Early Vs. Expectant Management of Spina Bifida Patients-Are We All Talking About a Risk Stratified Approach?

机构信息

Department of Urology, Division of Pediatric Urology, Children's Health System Texas, University of Texas Southwestern, Dallas, TX, USA.

出版信息

Curr Urol Rep. 2019 Nov 16;20(11):76. doi: 10.1007/s11934-019-0943-z.

Abstract

PURPOSE OF REVIEW

Advancements in the care of patients affected by myelomeningocele have flourished in recent years especially with respect to renal preservation and continence. Involvement of urologists both prenatally and early in life has driven many developments in preventative care and early intervention. As of yet, however, the ideal management algorithm that offers these patients the least invasive diagnostic testing and interventions while still preserving renal and bladder function remains ill defined.

RECENT FINDINGS

In a shift from prior years where the use of surgical intervention and intermittent catheterization were more liberally employed, some providers have more recently advocated for monitoring patients in a more conservative manner with a variety of diagnostic tests until radiographic or clinical changes are discovered. The criteria used to define the need for catheterization and the timing to initiate CIC or more invasive interventions is disparate across pediatric urology and there is published data to support several approaches. This review presents some of these criteria for use of CIC and some newer evidence to support different approaches along with supporting the trend toward individualized medicine and use of risk stratification in developing clinical treatment algorithms.

摘要

目的综述

近年来,脊髓脊膜膨出患者的护理取得了进展,尤其是在肾脏保护和控尿方面。产前和早期泌尿科医生的参与推动了许多预防性护理和早期干预的发展。然而,目前为止,为这些患者提供既能提供最少侵入性诊断测试和干预,同时又能保留肾脏和膀胱功能的理想管理算法仍未明确。

最新发现

与前几年更自由地使用手术干预和间歇性导尿不同,一些医生最近更倾向于以更保守的方式监测患者,使用各种诊断测试,直到发现放射学或临床变化。在小儿泌尿科中,用于定义导尿需求和开始 CIC 或更具侵入性干预的时机的标准存在差异,并且有数据支持多种方法。本综述介绍了 CIC 的一些使用标准,以及一些支持不同方法的新证据,并支持个体化医学和使用风险分层制定临床治疗算法的趋势。

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