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社交认知中的组合催产素神经药理学。

Combinatorial Oxytocin Neuropharmacology in Social Cognition.

机构信息

Department of Psychology, Yale University, New Haven, CT, USA.

Department of Psychology, Yale University, New Haven, CT, USA; Department of Psychology, University of Turin, Torino, Italy.

出版信息

Trends Cogn Sci. 2020 Jan;24(1):8-12. doi: 10.1016/j.tics.2019.10.004. Epub 2019 Nov 14.

Abstract

The efficacy and reliability of using intranasal oxytocin (OT) to clinically enhance social functions remains undependable. We discuss the potential benefit of concurrent administration of OT and naloxone (NAL) to robustly modulate social behavior. We further suggest that combinatorial neuropharmacology approaches should exploit the interactions between OT and serotonin to regulate social functions.

摘要

经鼻给予催产素(OT)以临床增强社会功能的疗效和可靠性尚不可靠。我们讨论了同时给予 OT 和纳洛酮(NAL)以有力调节社会行为的潜在益处。我们进一步建议,组合神经药理学方法应利用 OT 和 5-羟色胺之间的相互作用来调节社会功能。

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