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三尖瓣环平面收缩期位移(TAPSE)在肺栓塞患者风险分层和预后预测中的应用。

Tricuspid Annular Plane Systolic Excursion (TAPSE) for Risk Stratification and Prognostication of Patients with Pulmonary Embolism.

机构信息

Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.

Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

出版信息

J Emerg Med. 2020 Mar;58(3):449-456. doi: 10.1016/j.jemermed.2019.09.017. Epub 2019 Nov 15.

Abstract

BACKGROUND

The categorization of pulmonary embolism (PE) as non-massive, sub-massive, and massive helps guide acute management. The presence of right ventricular (RV) strain differentiates sub-massive from non-massive PEs. Unlike laboratory markers and electrocardiogram changes, the classic parameters used in the echocardiographic diagnosis of RV strain have a technical component that is operator-dependent.

OBJECTIVE

This narrative review will describe the physiologic effects of a PE on the RV and how this affects prognosis. It will summarize the literature evaluating the accuracy and prognostic ability of tricuspid annular plane systolic excursion (TAPSE) in the echocardiographic assessment of RVfunction. The review will describe the appeal of TAPSE for this purpose, provide cutoff measurements, and then illustrate how to perform the technique itself, while offering associated pearls and pitfalls in this bedside evaluation.

DISCUSSION

RV function and dynamics undergo acute changes in the setting of a PE. RV dysfunction predicts poor outcomes in both the short and long term. However, RV strain is difficult to capture on echocardiography due to the chamber's complex geometric shape and contraction. From the apical four-chamber window, TAPSE offers a quantitative measure that is more easily performed with high interobserver reliability for evaluating systolic RV contraction. This measurement carries prognostic value in patients diagnosed with PE.

CONCLUSIONS

Along with other more qualitative echocardiographic parameters, TAPSE can be used as a simple quantitative measure of RV dysfunction for differentiating sub-massive from non-massive PEs. This categorization helps guide acute management and disposition.

摘要

背景

肺栓塞(PE)的分类为非大块、亚大块和大块,有助于指导急性管理。右心室(RV)应变的存在将亚大块与非大块 PE 区分开来。与实验室标志物和心电图变化不同,超声心动图诊断 RV 应变中使用的经典参数具有技术成分,这取决于操作者。

目的

本叙述性综述将描述 PE 对 RV 的生理影响,以及这如何影响预后。它将总结评估三尖瓣环平面收缩期位移(TAPSE)在超声心动图评估 RV 功能中的准确性和预后能力的文献。该综述将描述 TAPSE 用于此目的的吸引力,提供截止测量值,然后说明如何执行该技术本身,同时在该床边评估中提供相关技巧和陷阱。

讨论

在 PE 情况下,RV 功能和动力学会发生急性变化。RV 功能障碍预测短期和长期预后不良。然而,由于心室的复杂几何形状和收缩,RV 应变在超声心动图上很难捕捉。从心尖四腔窗,TAPSE 提供了一种定量测量值,对于评估收缩期 RV 收缩的观察者间可靠性更高。该测量值在诊断为 PE 的患者中具有预后价值。

结论

除了其他更定性的超声心动图参数外,TAPSE 可用于作为区分亚大块与非大块 PE 的 RV 功能障碍的简单定量测量值。这种分类有助于指导急性管理和处置。

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