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小儿气管切开术的流行病学和不良结局的危险因素:一项 11 年单中心经验。

Epidemiology of Pediatric Tracheostomy and Risk Factors for Poor Outcomes: An 11-Year Single-Center Experience.

机构信息

Lee Kong Chian School of Medicine, National Technological University, Singapore.

Department of Paediatrics, KK Women's and Children's Hospital, Singapore.

出版信息

Otolaryngol Head Neck Surg. 2020 Jan;162(1):121-128. doi: 10.1177/0194599819887096. Epub 2019 Nov 19.

Abstract

OBJECTIVE

Children with long-term tracheostomies are at higher risk of complications. This study aims to describe the epidemiology, outcomes, and factors associated with successful decannulation in children undergoing tracheostomy.

STUDY DESIGN

Case series with chart review.

SETTING

Tertiary hospital.

SUBJECTS AND METHODS

A retrospective analysis was conducted on pediatric tracheostomies performed from 2006 to 2016. Demographics, preexisting comorbidities, indications for tracheostomy, and pretracheostomy ventilatory requirements were collected. A multivariate regression model with covariates of age, failure to thrive (FTT), and comorbidities was used to identify factors associated with successful decannulation. Secondary outcomes were ventilation and oxygen requirements at hospital discharge, hospital and intensive care unit length of stay, and complications.

RESULTS

In total, 105 patients received a tracheostomy at a median age of 8.0 months (interquartile range, 2.0-45.0). The most common indication was anatomic airway obstruction (55 of 105, 52.5%). Forty-four (41.9%) patients had preexisting FTT. In-hospital mortality was 14 of 105 (13.3%). None were directly related to tracheostomy. At discharge, 40 of 91 (44.0%) and 12 of 91 (13.2%) required home mechanical ventilation and supplemental oxygen, respectively. Forty-one (39%) patients underwent successful decannulation at a median 408 days (interquartile range, 170-1153) posttracheostomy. On adjusted analysis, unsuccessful decannulation was more common in patients with FTT and neurologic comorbidities. Postoperative complications were more common in younger patients and those with a longer time to decannulation.

CONCLUSION

Neurologic comorbidities and FTT were risk factors for unsuccessful decannulation after pediatric tracheostomy. Nutritional interventions may have a role in improving long-term outcomes following pediatric tracheostomies and should be investigated in future studies.

摘要

目的

长期气管切开的儿童发生并发症的风险较高。本研究旨在描述行气管切开术的儿童的流行病学、结局和与成功拔管相关的因素。

研究设计

病例系列,回顾性分析。

设置

三级医院。

受试者和方法

对 2006 年至 2016 年期间进行的儿科气管切开术进行了回顾性分析。收集了人口统计学资料、既往合并症、气管切开术的适应证以及气管切开术前通气需求。采用多元回归模型,协变量包括年龄、生长发育迟缓(FTT)和合并症,以确定与成功拔管相关的因素。次要结局为出院时的通气和氧需求、住院和重症监护病房的住院时间以及并发症。

结果

共有 105 例患者在中位年龄 8.0 个月(四分位距,2.0-45.0)时接受了气管切开术。最常见的适应证是解剖气道阻塞(55/105,52.5%)。44 例(41.9%)患者有既往 FTT。院内死亡率为 105 例中的 14 例(13.3%)。均与气管切开术无关。出院时,91 例患者中有 40 例(44.0%)和 12 例(13.2%)需要家庭机械通气和补充氧气。41 例(39%)患者在气管切开术后中位 408 天(四分位距,170-1153)成功拔管。在调整分析中,FTT 和神经合并症患者的拔管失败更为常见。术后并发症在较年轻的患者和需要更长时间拔管的患者中更为常见。

结论

神经合并症和 FTT 是儿科气管切开术后拔管失败的危险因素。营养干预可能在改善儿科气管切开术后的长期结局方面发挥作用,应在未来的研究中进行探讨。

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