Department of Anesthesiology, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, USA.
Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Spine J. 2020 Apr;20(4):547-555. doi: 10.1016/j.spinee.2019.11.009. Epub 2019 Nov 16.
Vertebral augmentation procedures are used for treatment of osteoporotic compression fractures. Prior studies have reported disparities in the treatment of patients with osteoporotic vertebral fractures, particularly with regards to the use of vertebroplasty and kyphoplasty.
The purpose of this study is to report updates in racial and health insurance inequalities of spine augmentation procedures in patients with osteoporotic fractures.
With the use of the National Inpatient Sample, we identified hospitalized patients with osteoporotic fractures between the period of 2011 and 2015. Patients with spine augmentation, defined by the utilization of vertebroplasty and kyphoplasty, were also identified. Our primary outcome was defined as the utilization of spine augmentation procedures across ethnic (white, hispanic, black, and asian/pacific islander) and insurance (self-pay, private insurance, Medicare, and Medicaid) groups. Variables were identified from the NIS database using International Classification of Diseases, Ninth and Tenth diagnosis codes. Univariate and multivariate regression analysis was used for statistical analysis with p value <.05 considered significant. A subgroup analysis was performed across the utilization of kyphoplasty, vertebroplasty, and Medicare coverage.
We identified a total of 110,028 patients with a primary diagnosis of vertebral fracture between 2011 and 2015 (mean age: 74.4±13.6 years, 68% women). About 16,237 patients (14.8%) underwent any type of spine augmentation with over 75% of the patients receiving kyphoplasty. Multivariate analysis showed that black patients (odds ratio [OR]=0.64, 95% confidence interval [CI]: 0.58-0.70, p<.001), Hispanic patients (OR=0.79, 95% CI: 0.73-0.86, p<.001), and Asian/Pacific Islander (OR=0.79, 95% CI: 0.70-0.89, p<.001) had significantly lower odds for receiving any spine augmentation compared with white patients. Patients with Medicaid (OR=0.59, 95% CI: 0.53-0.66, p<.001), private insurance (OR=0.90, 95% CI: 0.85-0.96, p=.001), and those who self-pay (OR=0.57, 95% CI: 0.47-0.69, p<.001) had significantly lower odds of spine augmentation compared with those with Medicare. Comparative use of kyphoplasty was not significantly different between white and black patients (OR=0.85, 95% CI: 0.70-1.04, p=.12). However, Hispanic patients (OR=0.84, 95% CI: 0.71-0.99, p=.04) and Asian/Pacific Islander patients (OR=0.73, 95% CI: 0.58-0.92, p=.007) had significantly lower use of kyphoplasty compared with white patients. The comparative use of kyphoplasty among patients receiving spine augmentation was not significantly different across each insurances status when compared with patients with Medicare.
Our study suggests that racial and socioeconomic disparities continue to exist with the utilization of spine augmentation procedures in hospitalized patients with osteoporotic fractures.
椎体增强术用于治疗骨质疏松性压缩性骨折。先前的研究报告了骨质疏松性椎体骨折患者治疗方面的差异,特别是在使用椎体成形术和后凸成形术方面。
本研究旨在报告骨质疏松性骨折患者脊柱增强手术中种族和健康保险不平等情况的最新变化。
利用国家住院患者样本,我们确定了 2011 年至 2015 年期间患有骨质疏松性骨折的住院患者。还确定了使用椎体成形术和后凸成形术的脊柱增强患者。我们的主要结果是定义为跨种族(白种人、西班牙裔、黑人和亚裔/太平洋岛民)和保险(自付、私人保险、医疗保险和医疗补助)群体的脊柱增强程序的使用情况。变量是使用国家住院患者样本数据库中的国际疾病分类、第九和第十诊断代码确定的。使用 p 值<.05 的单变量和多变量回归分析进行统计分析。进行了亚组分析,分析了后凸成形术、椎体成形术和医疗保险覆盖的利用情况。
我们确定了 2011 年至 2015 年间共有 110028 名原发性椎体骨折患者(平均年龄:74.4±13.6 岁,68%为女性)。约有 16237 名(14.8%)患者接受了任何类型的脊柱增强术,其中超过 75%的患者接受了后凸成形术。多变量分析显示,黑人患者(比值比[OR]=0.64,95%置信区间[CI]:0.58-0.70,p<.001)、西班牙裔患者(OR=0.79,95% CI:0.73-0.86,p<.001)和亚裔/太平洋岛民(OR=0.79,95% CI:0.70-0.89,p<.001)接受任何脊柱增强的可能性明显低于白人患者。有医疗补助(OR=0.59,95% CI:0.53-0.66,p<.001)、私人保险(OR=0.90,95% CI:0.85-0.96,p=.001)和自付(OR=0.57,95% CI:0.47-0.69,p<.001)的患者接受脊柱增强的可能性明显低于有医疗保险的患者。白人和黑人患者之间比较使用后凸成形术的差异无统计学意义(OR=0.85,95% CI:0.70-1.04,p=.12)。然而,西班牙裔患者(OR=0.84,95% CI:0.71-0.99,p=.04)和亚裔/太平洋岛民患者(OR=0.73,95% CI:0.58-0.92,p=.007)使用后凸成形术的可能性明显低于白人患者。与医疗保险患者相比,接受脊柱增强的患者之间使用后凸成形术的比较在每个保险状态下没有显著差异。
我们的研究表明,在患有骨质疏松性骨折的住院患者中,脊柱增强手术的使用仍然存在种族和社会经济差异。