Franchi F, Padeletti L, Brat A, Michelucci A, Arcangeli C, Fantini F
Acta Cardiol. 1979;34(6):385-99.
Sinus node function was evaluated in 18 patients with sinus bradycardia without complaints (Group I), in 16 patients with sinus bradycardia and/or sinoatrial block with complaints (subgroup IIa) and in 14 patients with the bradycardia-tachycardia syndrome (subgroup IIb). Mean values of corrected sinus node recovery time (CSRT), atrial effective refractory period (AERP) and atrial functional refractory period (AFRP) differentiated significatively asymptomatic subjects of group I from the two subgroups of patients with sinoatrial disease, but failed to differentiate each subgroup from the other one. There was no significative difference in mean sinoatrial conduction time (SACT) between group I and each of the two subgroups. Three patients of subgroup IIa and 1 patient of subgroup IIb had a false negative response after both overdrive and premature programmed atrial pacing. Spontaneous cycle length was directly correlated with the sinus node recovery time and the atrial refractoriness in group I, and with the only sinus node recovery time in subgroup IIb. No direct correlations were observed in subgroup IIa. This suggests a less disturbed sinus node automaticity in bradycardia-tachycardia syndrome.
对18例无不适症状的窦性心动过缓患者（I组）、16例有症状的窦性心动过缓及/或窦房阻滞患者（IIa亚组）和14例心动过缓-心动过速综合征患者（IIb亚组）进行了窦房结功能评估。校正窦房结恢复时间（CSRT）、心房有效不应期（AERP）和心房功能不应期（AFRP）的平均值，显著区分了I组无症状受试者与窦房疾病的两个患者亚组，但未能区分每个亚组与另一个亚组。I组与两个亚组中的每一个亚组之间的平均窦房传导时间（SACT）无显著差异。IIa亚组的3例患者和IIb亚组的1例患者在超速和早搏程控心房起搏后出现假阴性反应。I组中，自发周期长度与窦房结恢复时间和心房不应期直接相关，而在IIb亚组中仅与窦房结恢复时间直接相关。IIa亚组未观察到直接相关性。这表明心动过缓-心动过速综合征中窦房结自律性受干扰较小。
