Berić Aleksandar, Dimitrijević Milan R, Lindblom Ulf
Division of Restorative Neurology and Human Neurobiology, Baylor College of Medicine, Houston, TXU.S.A. Department of Neurology, Karolinska Hospital, StockholmSweden.
Pain. 1988 Aug;34(2):109-116. doi: 10.1016/0304-3959(88)90155-8.
We have described 13 spinal cord injury patients with a complaint of diffuse, ongoing dysesthesias below the level of the lesion, which are burning in quality, and usually functionally limiting. Quantitative sensory and neurophysiological testing revealed relative preservation of the dorsal column functions in comparison to absence of spinothalamic system mediated functions. On the basis of these findings, we are speculating that such an imbalance between the spinothalamic and dorsal column systems is the main underlying mechanism of dysesthesias as a central nervous system misinterpretation of residual peripheral input.
我们描述了13例脊髓损伤患者，他们主诉损伤平面以下存在弥漫性、持续性感觉异常，性质为灼痛，且通常会限制功能。定量感觉和神经生理学测试显示，与脊髓丘脑系统介导的功能缺失相比，薄束功能相对保留。基于这些发现，我们推测脊髓丘脑系统和薄束系统之间的这种失衡是感觉异常的主要潜在机制，即中枢神经系统对残留外周输入的错误解读。
