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是手术还是阻滞?上肢手术后神经损伤的发生率、危险因素及结局

Is It the Surgery or the Block? Incidence, Risk Factors, and Outcome of Nerve Injury following Upper Extremity Surgery.

作者信息

Droog Wouter, Lin D-Yin, van Wijk Jan J, Ho-Asjoe Raissah C H, Coert J Henk, Stolker Robert Jan, Galvin Eilish M

机构信息

Department of Anesthesiology, Erasmus University Medical Center Rotterdam, The Netherlands.

Department of Plastic Surgery, University Medical Centre Utrecht, The Netherlands.

出版信息

Plast Reconstr Surg Glob Open. 2019 Sep 25;7(9):e2458. doi: 10.1097/GOX.0000000000002458. eCollection 2019 Sep.

Abstract

UNLABELLED

Although numerous studies have addressed the topic of postoperative nerve injury, debate continues to exist on its exact incidence, risk factors, etiology, and functional outcome. The aim of this study is to investigate the incidence of nerve injury and to identify patient, anesthetic, and surgical factors pertaining to perioperative nerve injury. Also, long-term nerve injury outcomes were assessed in terms of functionality.

METHODS

A total of 297 patients, scheduled for elective distal upper extremity surgery, were prospectively included. At various time points, patients were screened for new onset nerve injury by means of clinical examination and questionnaires (including the Quick Disabilities of the Arm, Shoulder and Hand functionality measure).

RESULTS

New nerve injury was diagnosed in 14 patients [4.7% (95% CI, 2.8-7.8)], but no causative risk factors were identified. The exact origin of nerve injury is suspected to be surgical in 11 cases. At 4 years postoperatively, 5 of the 14 patients with nerve injury (36%) were still symptomatic and had reduced functionality relative to preoperative status.

CONCLUSIONS

This study demonstrates an incidence of all cause nerve injury of 4.7%. No specific patient, anesthetic, or surgical risk factors are identified and, importantly, patients who received regional anesthesia are not at more risk of nerve injury than those who received general anesthesia. The exact origin of nerve injury is very difficult to determine, but is suspected to be caused by direct surgical trauma in most cases. Four years following the nerve injury, approximately 40% of the patients with new onset nerve injury have reduced functionality.

摘要

未标注

尽管众多研究都涉及术后神经损伤这一话题,但关于其确切发病率、危险因素、病因及功能转归仍存在争议。本研究的目的是调查神经损伤的发病率,并确定与围手术期神经损伤相关的患者、麻醉和手术因素。此外,还从功能方面评估了长期神经损伤的转归。

方法

前瞻性纳入了297例计划行择期上肢远端手术的患者。在不同时间点,通过临床检查和问卷调查(包括手臂、肩部和手部功能快速残疾测量)对患者进行新发神经损伤筛查。

结果

14例患者被诊断为新发神经损伤[4.7%(95%CI,2.8 - 7.8)],但未发现致病危险因素。11例神经损伤的确切原因被怀疑是手术所致。术后4年,14例神经损伤患者中有5例(36%)仍有症状,且相对于术前状态功能有所下降。

结论

本研究显示所有原因导致的神经损伤发病率为4.7%。未发现特定的患者、麻醉或手术危险因素,重要的是,接受区域麻醉的患者发生神经损伤的风险并不高于接受全身麻醉的患者。神经损伤的确切原因很难确定,但在大多数情况下怀疑是由直接手术创伤引起的。神经损伤4年后,约40%的新发神经损伤患者功能有所下降。

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