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钕钇铝石榴石激光(532纳米绿色)与二极管激光(810纳米)光凝治疗早产儿视网膜病变的比较:并发症方面的评估

Comparison of Nd:YAG laser (532 nm green) vs diode laser (810 nm) photocoagulation in the treatment of retinopathy of prematurity: an evaluation in terms of complications.

作者信息

Dikci Seyhan, Demirel Soner, Fırat Penpe Gül, Yılmaz Turgut, Ceylan Osman Melih, Bağ Harika Gözde Gözükara

机构信息

Department of Ophthalmology, İnönü University Turgut Özal Medical Center, Malatya, Turkey.

Department of Ophthalmology, Medical Park Hospital, Elazığ, Turkey.

出版信息

Lasers Med Sci. 2020 Aug;35(6):1323-1328. doi: 10.1007/s10103-019-02918-x. Epub 2019 Nov 19.

DOI:10.1007/s10103-019-02918-x
PMID:31745685
Abstract

PURPOSE

To compare the anterior and posterior segment complications of diode (810 nm) laser photocoagulation (LPC) and Nd:YAG (532 nm green) LPC in the treatment of retinopathy of prematurity (ROP).

PATIENTS AND METHODS

The 84 eyes of 43 patients treated with diode LPC (group 1) and 58 eyes of 31 patients treated with Nd:YAG LPC (group 2) for ROP in our clinic were enrolled in the study. Medical records of all patients were investigated retrospectively. The patients in each group were examined in terms of birth weights, gestational weeks, stage of retinopathy, number of lasers pots, laser parameters, and anterior and posterior complications of LPC.

RESULTS

The mean birth weeks of group 1 patients were postmenstrual 27.7 ± 2.5 (23-33), while the mean birth weights were 1006.0 ± 334.5 (540-1980) grams. The mean birth weeks of group 2 patients were postmenstrual 27.4 ± 2.6 (23-33), while the mean birth weights were 1073.8 ± 329.2 (480-1720) grams. The mean numbers of laser spots were 1036.0 ± 515.2 (430-2410) in group 1 per eye, while the mean numbers of laser spots were 1085.4 ± 526.0 (445-2530) in group 2 per eye (p ≥ 0.05). Additional laser application was performed in four eyes (4.8%) in group 1 and four eyes (6.9%) in group 2. Four eyes (4.8%) treated with diode LPC and one eye (1.7%) treated with Nd:YAG laser developed retinal detachment. Two eyes of a patient (3.4%) applied Nd:YAG LPC developed cataract.

CONCLUSION

Cataract may develop when Nd:YAG laser is used; however, posterior segment complications may be more likely to appear with the use of diode laser in these cases.

摘要

目的

比较二极管(810纳米)激光光凝术(LPC)和钕钇铝石榴石(532纳米绿色)激光光凝术治疗早产儿视网膜病变(ROP)时眼前段和眼后段并发症的情况。

患者与方法

本研究纳入了在我院接受二极管激光光凝术治疗的43例患者的84只眼(第1组)和接受钕钇铝石榴石激光光凝术治疗的31例患者的58只眼(第2组)用于ROP治疗。对所有患者的病历进行回顾性调查。对每组患者的出生体重、孕周、视网膜病变分期、激光光斑数量、激光参数以及激光光凝术的眼前段和眼后段并发症进行检查。

结果

第1组患者的平均出生孕周为孕龄27.7±2.5周(23 - 33周),平均出生体重为1006.0±334.5克(540 - 1980克)。第2组患者的平均出生孕周为孕龄27.4±2.6周(23 - 33周),平均出生体重为1073.8±329.2克(480 - 1720克)。第1组每只眼的平均激光光斑数量为1036.0±515.2个(430 - 2410个),第2组每只眼的平均激光光斑数量为1085.4±526.0个(445 - 2530个)(p≥0.05)。第1组有4只眼(4.8%)和第2组有4只眼(6.9%)进行了额外的激光治疗。接受二极管激光光凝术治疗的4只眼(4.8%)和接受钕钇铝石榴石激光治疗的1只眼(1.7%)发生了视网膜脱离。接受钕钇铝石榴石激光光凝术治疗的1例患者的2只眼(3.4%)发生了白内障。

结论

使用钕钇铝石榴石激光可能会发生白内障;然而,在这些病例中,使用二极管激光时眼后段并发症可能更易出现。

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引用本文的文献

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Retinopathy of Prematurity: Advances in the Screening and Treatment of Retinopathy of Prematurity Using a Single Center Approach.早产儿视网膜病变:采用单中心方法筛查和治疗早产儿视网膜病变的进展。
Am J Ophthalmol. 2022 Jan;233:189-215. doi: 10.1016/j.ajo.2021.07.016. Epub 2021 Jul 21.