Epsylon, Paul Valéry University, Montpellier, France.
Neurology Department, Parkinson's Disease Expert Centre, Gui de Chauliac Hospital, Montpellier, France.
J Clin Psychol. 2020 Mar;76(3):356-376. doi: 10.1002/jclp.22883. Epub 2019 Nov 20.
To test the efficacy of cognitive behavioral therapy for insomnia (CBT-i) in Parkinson's Disease (PD) and to evaluate its impact on indices of daytime and psychological functioning.
Fifteen patients with insomnia disorder (ID) comorbid to PD were enrolled in a single-case design with multiple baselines. Total wake time, sleep efficiency, and daytime sleepiness were recorded on a sleep diary. Self-reported measures of insomnia, anxiety and depressive symptoms, health-related quality of life, and psychological variables perpetuating ID were completed. All patients also underwent a clinical interview for ID diagnosis.
CBT-i was associated with significant changes in sleep variables and ID criteria. Significant positive treatment-related effects were also noted for all indices of daytime and psychological functioning, and for variables perpetuating ID. All of these improvements were well maintained at 3-month follow-up.
CBT-i is a promising therapeutic avenue for patients with PD.
测试认知行为疗法（CBT-i）治疗帕金森病（PD）伴发失眠的疗效，并评估其对日间和心理功能指标的影响。
15 名伴有失眠障碍（ID）的 PD 患者参与了一项单病例设计的多项基线研究。总清醒时间、睡眠效率和日间嗜睡均通过睡眠日记记录。使用自我报告的失眠、焦虑和抑郁症状、健康相关生活质量以及加重 ID 的心理变量评估方法完成评估。所有患者还接受了 ID 诊断的临床访谈。
CBT-i 与睡眠变量和 ID 标准的显著变化相关。日间和心理功能的所有指标以及加重 ID 的变量也显示出显著的治疗相关积极效果。所有这些改善在 3 个月的随访中都得到了很好的维持。
CBT-i 是 PD 患者有前途的治疗途径。
