一氧化二氮与人类状态依赖记忆。

Nitrous oxide and human state-dependent memory.

作者信息

Mewaldt S P, Ghoneim M M, Choi W W, Korttila K, Peterson R C

机构信息

Department of Psychology, Marshall University, Huntington, WV 25755-2672.

出版信息

Pharmacol Biochem Behav. 1988 May;30(1):83-7. doi: 10.1016/0091-3057(88)90428-5.

DOI:10.1016/0091-3057(88)90428-5

PMID:3174757

Abstract

State-dependent effects of nitrous oxide on human memory were examined by administering serial and paired-associate learning tasks to subjects receiving 20 and 30% nitrous oxide or placebo. Nitrous oxide in 30% concentration impaired learning of both tasks. In addition, it produced an atypical form of asymmetric state-dependent memory; subjects who learned while receiving placebo and recalled while receiving nitrous oxide displayed the worst recall.

摘要

通过对接受20%和30%氧化亚氮或安慰剂的受试者进行系列学习和配对联想学习任务，研究了氧化亚氮对人类记忆的状态依赖性效应。30%浓度的氧化亚氮损害了两项任务的学习效果。此外，它还产生了一种非典型的不对称状态依赖性记忆；在接受安慰剂时学习、在接受氧化亚氮时回忆的受试者表现出最差的回忆效果。