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用于鼓室成形术去上皮化的CO激光

CO Laser for De-epithelialization in Tympanoplasty.

作者信息

Nair Lakshmi, Gildener-Leapman Neil, Parnes Steven

机构信息

1Albany Medical College, 47 New Scotland Ave, Albany, NY 12208 USA.

2Division of Otolaryngology, Albany Medical College, Albany, NY USA.

出版信息

Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1364-1368. doi: 10.1007/s12070-018-1430-4. Epub 2018 Jun 21.

DOI:10.1007/s12070-018-1430-4
PMID:31750178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6841804/
Abstract

Tympanoplasty repairs tympanic membrane perforations but also covers an umbrella of procedures characterized by surgery of the mastoid bone. Tympanoplasty is widely regarded as a beneficial procedure with an over 90% graft closure success rate and an over 80% return to normal hearing range. Though surgical technique and graft type are important in determining surgical outcomes of the procedure, results are most greatly correlated with location of the perforation. Marginal perforations are associated with the most complications in reconstruction of the tympanic membrane, lack of vascularization and limited membrane area delaying the healing process (4). Lasers have been used in medical procedures dating back to the 1960s. The advantage of infrared lasers such as CO are the precision of cutting and the smooth interaction with tissues (5). The CO laser is absorbed by the tympanic membrane and does not damage the middle ear while visible lasers penetrate and can damage the ear drum (6). This retrospective study of 150 patients from 2013-2016 assesses and demonstrates the viability of using carbon dioxide laser as an alternative to the traditional method for de-epithelialization of tympanic perforation margins during tympanoplasty. By comparing closure rates and audiogram data, this study reveals parameters of use, benefits and adverse outcomes on healing and hearing restoration with the CO laser-assisted method. Perforation closure rate of 91% and hearing improvement in 66% of patients was observed. Fourteen patients did not undergo closure of the tympanic membrane with an overwhelming majority of the 14 having large and marginal perforations.

摘要

鼓室成形术不仅可修复鼓膜穿孔,还涵盖了一系列以乳突骨手术为特征的手术。鼓室成形术被广泛认为是一种有益的手术,移植物闭合成功率超过90%,听力恢复到正常范围的比例超过80%。虽然手术技术和移植物类型对该手术的手术结果很重要,但结果与穿孔的位置相关性最大。边缘性穿孔在鼓膜重建中并发症最多,血管化不足和膜面积有限会延迟愈合过程(4)。激光自20世纪60年代起就已用于医疗手术。诸如CO等红外激光的优点是切割精确且与组织相互作用平稳(5)。CO激光被鼓膜吸收,不会损伤中耳,而可见激光会穿透并可能损伤鼓膜(6)。这项对2013年至2016年150例患者的回顾性研究评估并证明了在鼓室成形术期间使用二氧化碳激光替代传统方法对鼓膜穿孔边缘进行上皮化剥脱的可行性。通过比较闭合率和听力图数据,本研究揭示了CO激光辅助方法在愈合和听力恢复方面的使用参数、益处和不良后果。观察到穿孔闭合率为91%,66%的患者听力得到改善。14例患者鼓膜未闭合,其中绝大多数有大的边缘性穿孔。

相似文献

1
CO Laser for De-epithelialization in Tympanoplasty.用于鼓室成形术去上皮化的CO激光
Indian J Otolaryngol Head Neck Surg. 2019 Nov;71(Suppl 2):1364-1368. doi: 10.1007/s12070-018-1430-4. Epub 2018 Jun 21.
2
[CO2-laser-assisted de-epithelialization of perforation margins of persistent tympanic membrane perforations. An alternative to conventional surgical procedures].[二氧化碳激光辅助持续性鼓膜穿孔边缘上皮去除术。传统外科手术的替代方法]
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Impact of mastoidectomy on simple tympanic membrane perforation repair.乳突切除术对单纯鼓膜穿孔修复的影响
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Otol Neurotol. 2019 Mar;40(3):e173-e177. doi: 10.1097/MAO.0000000000002147.
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Endoscopic vs Microscopic Overlay Tympanoplasty for Correcting Large Tympanic Membrane Perforations: A Randomized Clinical Trial.内镜下与显微镜下覆盖式鼓室成形术治疗大鼓膜穿孔的随机临床试验。
Otolaryngol Head Neck Surg. 2018 Nov;159(5):879-886. doi: 10.1177/0194599818786948. Epub 2018 Jul 10.
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Air space reduction tympanomastoidectomy repairs difficult perforations more reliably than tympanoplasty.鼓室成形术修复困难性鼓膜穿孔的效果不如鼓室成形术。
Laryngoscope. 2014 Jun;124 Suppl 3:S1-13. doi: 10.1002/lary.23599. Epub 2013 Apr 2.
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Butterfly cartilage graft inlay tympanoplasty for large perforations.蝶形软骨移植片内嵌式鼓室成形术治疗大穿孔
Laryngoscope. 2006 Oct;116(10):1813-6. doi: 10.1097/01.mlg.0000231742.11048.ed.
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Type-I Tympanoplasty By Underlay Technique - Factors Affecting Outcome.
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The button graft technique for perforations affecting less than 25% of the tympanic membrane: a non-randomised comparison of a new modification to cartilage tympanoplasty with underlay and overlay grafts.纽扣法鼓膜修补术治疗小于 25%鼓膜穿孔:软骨鼓膜成形术加下置和后置移植物的新型改良与传统方法的非随机比较。
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Mediolateral graft tympanoplasty for anterior or subtotal tympanic membrane perforation.用于鼓膜前部或大部分穿孔的中外侧移植鼓室成形术。
Otolaryngol Head Neck Surg. 2005 Apr;132(4):532-6. doi: 10.1016/j.otohns.2004.10.018.

本文引用的文献

1
Outcomes of type I tympanoplasty using a cartilage shield graft in patients with poor prognostic factors.使用软骨盾形移植片对预后因素较差的患者进行I型鼓室成形术的结果。
Auris Nasus Larynx. 2017 Oct;44(5):517-521. doi: 10.1016/j.anl.2016.10.013. Epub 2016 Dec 8.
2
Evaluation of Factors Affecting the Surgical Outcome in Tympanoplasty.鼓室成形术手术结果的影响因素评估
Iran J Otorhinolaryngol. 2016 Mar;28(85):99-104.
3
Use of the flexible fiber CO2 laser in pediatric transcanal endoscopic middle ear surgery.柔性光纤二氧化碳激光在小儿经耳道内镜中耳手术中的应用。
Int J Pediatr Otorhinolaryngol. 2016 Jun;85:154-7. doi: 10.1016/j.ijporl.2016.03.039. Epub 2016 Apr 11.
4
Prognostic factors in type I tympanoplasty.I型鼓室成形术的预后因素
Auris Nasus Larynx. 2015 Feb;42(1):20-3. doi: 10.1016/j.anl.2014.08.010. Epub 2014 Aug 30.
5
Pre-Operative and Post-Operative Assessment of Hearing following Tympanoplasty.鼓室成形术后听力的术前与术后评估
Indian J Otolaryngol Head Neck Surg. 2012 Dec;64(4):377-81. doi: 10.1007/s12070-011-0331-6. Epub 2011 Dec 7.
6
Tympanoplasty: an up-to-date pictorial review.鼓室成形术:最新的影像学综述。
J Neuroradiol. 2012 Jul;39(3):149-57. doi: 10.1016/j.neurad.2011.05.004. Epub 2011 Jul 2.
7
Revision surgery for chronic otitis media: characteristics and outcomes in comparison with primary surgery.慢性中耳炎翻修手术:与初次手术相比的特点及结果
Auris Nasus Larynx. 2010 Feb;37(1):18-22. doi: 10.1016/j.anl.2009.01.014. Epub 2009 Apr 26.
8
"Window shade" tympanoplasty for anterior marginal perforations.用于前边缘穿孔的“窗帘式”鼓室成形术
Laryngoscope. 2005 Sep;115(9):1655-9. doi: 10.1097/01.mlg.0000175067.19744.27.