光学相干断层扫描对近视患者后皮质前玻璃体囊和 Cloquet 管特征的研究。

Characteristics of Posterior Precortical Vitreous Pockets and Cloquet’s Canal in Patients with Myopia by Optical Coherence Tomography.

机构信息

Department of Retina Center, Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang Province, China.

出版信息

Invest Ophthalmol Vis Sci. 2019 Nov 1;60(14):4882-4888. doi: 10.1167/iovs.19-27426.

DOI:10.1167/iovs.19-27426

PMID:31752017

Abstract

PURPOSE

To describe the morphological features of posterior precortical vitreous pockets (PPVP) and Cloquet's Canal in patients with myopia using swept-source optical coherence tomography (SS OCT).

METHODS

A total of 96 eyes of 51 volunteers (range, 5-18 years) were enrolled in this study, and all individuals underwent OCT (Optovue Inc., Fremont, CA, USA) examinations. From the collected PPVPs images, the widths and heights of the PPVPs were measured, and connections between PPVPs and Cloquet's Canal were identified. The PPVPs widths and heights, width:height ratios and proportions of connections were compared among different age (5-8, 9-14, 15-18 years), axial length (AL; 21-23, 23-25, 25-29 mm) and myopia groups (hyperopia, low to moderate myopia, high myopia); the group data were analyzed to determine their relationship with myopia.

RESULTS

PPVPs were identified in 89 of 96 eyes; 6 eyes were excluded for poor image quality. The PPVPs width was positively correlated with age, especially in the low to moderate myopia group (F = 7.715, P = 0.001). There was a significant difference in the PPVPs height between the refractive error groups in the 9 to 14 years group (F = 4.905, P = 0.005). The PPVPs width:height ratio was different among the refractive error groups in the 9 to 14 years group (F = 3.335, P = 0.041) and among the different age groups in the low to moderate myopia group (F = 6.077, P = 0.004). A total of 22 eyes (22.4%) were identified as having a connection between the PPVP and Cloquet's Canal. The connections began to increase with AL at 5 to 8 years (χ2 = 7.363, P = 0.025).

CONCLUSIONS

PPVPs existed in most myopia patients from 5 to 18 years old. PPVPs width was positively correlated with age, especially in the low to moderate myopia group. PPVPs height decreased in the 9 to 14 years group with myopia. An imbalance in the horizontal and vertical enlargement of PPVP was the main feature in the 9- to 14-year-old group with myopia. The connections between the PPVP and Cloquet's Canal were associated with AL extension in the 5- to 8-year-old group.

摘要

目的

使用扫频源光学相干断层扫描（SS-OCT）描述近视患者后皮质玻璃体前腔（PPVP）和克洛凯氏管的形态特征。

方法

本研究共纳入 51 名志愿者的 96 只眼（5-18 岁），所有患者均接受 OCT（美国 Optovue 公司）检查。从收集到的 PPVP 图像中测量了 PPVP 的宽度和高度，并确定了 PPVP 与克洛凯氏管之间的连接。比较了不同年龄（5-8 岁、9-14 岁、15-18 岁）、眼轴长度（AL；21-23mm、23-25mm、25-29mm）和近视组（远视、低中度近视、高度近视）之间的 PPVP 宽度和高度、宽度：高度比和连接比例；对组数据进行分析以确定其与近视的关系。

结果

在 96 只眼中，有 89 只眼可识别出 PPVP；6 只眼因图像质量差而被排除。PPVP 的宽度与年龄呈正相关，尤其是在低中度近视组（F=7.715，P=0.001）。在 9 至 14 岁组的屈光不正组之间，PPVP 的高度存在显著差异（F=4.905，P=0.005）。在 9 至 14 岁组的屈光不正组和低中度近视组的不同年龄组中，PPVP 的宽度：高度比存在差异（F=3.335，P=0.041）。共发现 22 只眼（22.4%）的 PPVP 与克洛凯氏管之间存在连接。连接在 5 至 8 岁时开始随 AL 增加（χ2=7.363，P=0.025）。

结论

在 5 至 18 岁的大多数近视患者中存在 PPVP。PPVP 的宽度与年龄呈正相关，尤其是在低中度近视组。9 至 14 岁组近视患者的 PPVP 高度降低。在 9 至 14 岁的近视组中，PPVP 的水平和垂直扩大不平衡是主要特征。5 至 8 岁组的 PPVP 与克洛凯氏管之间的连接与 AL 延长有关。