Department of Surgery, Jeju National University Hospital, Jeju, Korea.
Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
J Pediatr Surg. 2020 Jul;55(7):1344-1346. doi: 10.1016/j.jpedsurg.2019.09.035. Epub 2019 Oct 24.
The aim of this study was to evaluate surgical site infection (SSI) rates related to implanted central venous catheters (ICVC) in pediatric hematology and oncology patients with respect to absolute neutrophil count (ANC) levels.
From January 2004 to December 2015, pediatric patients with ICVC insertion were investigated retrospectively. Patients were divided into four groups according to preoperative ANC levels and Granulocyte-colony stimulating factor (G-CSF) usage. Immediate and early surgical site infections were evaluated 7 and 30 days following surgery.
In total, 1143 patients were enrolled. Patients were placed into 4 groups: 930 patients in group 1 with an ANC≥500/μL without G-CSF, 149 in group 2 with an ANC≥500/μL after G-CSF usage, 36 in group 3 with an ANC<500/μL without G-CSF, and 28 in group 4 with an ANC<500/μL even after G-CSF administration. Rates of immediate and early SSIs were not statistically different between groups. In the two-group analysis (group 1 and 2 vs. 3 and 4), the number of immediate and early SSIs were not also different, respectively.
There was no correlation between ANC levels and immediate and early SSI occurrence after ICVC placement.
III.
本研究旨在评估植入中心静脉导管（ICVC）的儿科血液肿瘤患者的手术部位感染（SSI）发生率与绝对中性粒细胞计数（ANC）水平的关系。
回顾性研究 2004 年 1 月至 2015 年 12 月期间接受 ICVC 插入术的儿科患者。根据术前 ANC 水平和粒细胞集落刺激因子（G-CSF）的使用情况，将患者分为四组。术后第 7 天和第 30 天评估即时和早期手术部位感染。
共纳入 1143 例患者。患者分为 4 组：组 1（n=930）ANC≥500/μL 且未使用 G-CSF；组 2（n=149）ANC≥500/μL 且使用 G-CSF 后；组 3（n=36）ANC<500/μL 且未使用 G-CSF；组 4（n=28）ANC<500/μL 且即使使用 G-CSF 后。各组之间即时和早期 SSI 的发生率无统计学差异。在两组分析（组 1 和 2 与组 3 和 4）中，即时和早期 SSI 的数量也没有差异。
ANC 水平与 ICVC 放置后即时和早期 SSI 的发生之间没有相关性。
III。
