Doody Paul, Lord Janet M, Greig Carolyn A, Whittaker Anna C
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK
MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
BMJ Open. 2019 Nov 21;9(11):e031159. doi: 10.1136/bmjopen-2019-031159.
Frailty is a common and clinically significant condition in older adults, predominantly due to its association with adverse health outcomes such as hospitalisation, disability and mortality. Exercise interventions have been shown to be a beneficial treatment for frailty. However, more high-quality studies are needed to assess the feasibility and impact of these interventions in frail geriatric populations within different settings, and their impact on broader aspects of health and well-being.
This study will use a 2-week, interventional, independent measures research design in order to assess the feasibility and impact of two specially adapted exercise training interventions (a specially adapted resistance training intervention, and Move It Or Lose It: an established community-based exercise intervention for older adults) aimed at improving the multidimensional health and functional capacity of frail geriatric hospital inpatients.
This study has received a favourable ethical opinion by the Coventry and Warwickshire NHS Research Ethics Committee and sponsorship by the University of Birmingham after review by the sponsors research governance office. The findings will be disseminated through publication in open access scientific journals, public engagement events, online via social media, conference presentations and directly to study participants on request.
NCT03141866.
衰弱是老年人中一种常见且具有临床意义的状况，主要是因为它与诸如住院、残疾和死亡等不良健康结局相关。运动干预已被证明是治疗衰弱的有益方法。然而，需要更多高质量研究来评估这些干预措施在不同环境下对衰弱老年人群体的可行性和影响，以及它们对健康和幸福更广泛方面的影响。
本研究将采用为期2周的干预性独立测量研究设计，以评估两种特别调整的运动训练干预措施（一种特别调整的阻力训练干预措施，以及“动则不衰”：一种针对老年人的成熟的社区运动干预措施）的可行性和影响，这些措施旨在改善衰弱老年住院患者的多维度健康和功能能力。
本研究已获得考文垂和沃里克郡国民保健服务研究伦理委员会的有利伦理意见，并在主办方研究管理办公室审查后获得伯明翰大学的资助。研究结果将通过发表在开放获取科学期刊上、公众参与活动、通过社交媒体在线传播、会议报告以及应要求直接向研究参与者进行传播。
NCT03141866。
