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高级别卵巢癌患者细胞减灭术前的影像学检查。

Imaging before cytoreductive surgery in advanced ovarian cancer patients.

机构信息

Istituto Imaging Svizzera Italiana, Ente Ospedaliero Cantonale, Lugano, TI, Switzerland

Oncology Institute of Southern Switzerland, Bellinzona, TI, Switzerland.

出版信息

Int J Gynecol Cancer. 2020 Jan;30(1):133-138. doi: 10.1136/ijgc-2019-000819. Epub 2019 Nov 21.

Abstract

Appropriate and accurate pre-operative imaging in epithelial ovarian cancer patients may allow selection of patients that may mostly benefit either from primary cytoreductive surgery or from neoadjuvant chemotherapy. If the patient is considered suitable for upfront surgery, pre-operative imaging may help in planning the surgical approach, to forecast the operating time, and to estimate the need for other consulting specialists. Currently, computed tomography (CT) imaging is the standard of care for pre-operative evaluation of ovarian cancer patients; however, advanced magnetic resonance imaging (MRI) is emerging as a technique that may overcome the limitations of CT imaging, especially for small peritoneal deposits in difficult-to-resect sites. Positron emission tomography (PET)-CT imaging in the pre-operative setting is currently limited, whereas the use of the new hybrid technique PET-MRI is still under evaluation. Since criteria that may preclude optimal cytoreductive surgery may vary, depending on the aggressiveness of the surgical procedure and surgeon skill, multidisciplinary consensus conferences are the ideal platform to evaluate extent of the disease and surgical strategy.

摘要

在卵巢上皮性癌患者中进行适当且准确的术前影像学检查,可能有助于选择主要从初始肿瘤细胞减灭术或新辅助化疗中获益的患者。如果患者适合直接进行手术,术前影像学检查可能有助于规划手术入路,预测手术时间,并估计是否需要其他会诊专家。目前,计算机断层扫描(CT)成像被认为是卵巢癌患者术前评估的标准;然而,高级磁共振成像(MRI)作为一种可能克服 CT 成像局限性的技术正在出现,特别是对于难以切除部位的小腹膜沉积物。在术前应用中,正电子发射断层扫描(PET)-CT 成像目前受到限制,而新型混合技术 PET-MRI 的应用仍在评估中。由于可能排除最佳肿瘤细胞减灭术的标准可能因手术的侵袭性和外科医生的技术水平而异,因此多学科共识会议是评估疾病程度和手术策略的理想平台。

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