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万古霉素间隔物诱导的溶血。

Vancomycin Spacer-induced Hemolysis.

作者信息

Sudhakaran Anuraj, Baburaj Aparna, Banerjee Kinjal, Essrani Rajesh

机构信息

Internal Medicine, Geisinger Medical Center, Danville, USA.

Internal Medicine, Geisinger Medicine Center, Danville, USA.

出版信息

Cureus. 2019 Oct 6;11(10):e5848. doi: 10.7759/cureus.5848.

DOI:10.7759/cureus.5848
PMID:31754583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6830846/
Abstract

Intravenous vancomycin-induced hemolysis has been documented in the literature. This has been presumed to be due to the development of antibodies against additives that are added along with antibiotics. Herein, we present the case of a 72-year-old male who had hemolysis after the placement of vancomycin spacer, which improved after the spacer was removed.

摘要

静脉注射万古霉素引起的溶血在文献中已有记载。据推测,这是由于针对与抗生素一起添加的添加剂产生抗体所致。在此,我们报告一例72岁男性患者,其在放置万古霉素间隔物后发生溶血,在移除间隔物后病情好转。

相似文献

1
Vancomycin Spacer-induced Hemolysis.万古霉素间隔物诱导的溶血。
Cureus. 2019 Oct 6;11(10):e5848. doi: 10.7759/cureus.5848.
2
Vancomycin-Induced Hemolytic Anemia.万古霉素诱导的溶血性贫血
Cureus. 2023 May 18;15(5):e39191. doi: 10.7759/cureus.39191. eCollection 2023 May.
3
Drug-induced immune hemolytic anemia associated with anti-vancomycin complicated by a paraben antibody.药物诱导的免疫性溶血性贫血,与抗万古霉素相关,并合并对羟基苯甲酸酯抗体。
Transfusion. 2018 Jan;58(1):181-188. doi: 10.1111/trf.14362. Epub 2017 Oct 8.
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[Giant cell hepatitis and autoimmune hemolytic anemia: efficacy of splenectomy on hemolysis].[巨细胞性肝炎与自身免疫性溶血性贫血:脾切除术对溶血的疗效]
Arch Pediatr. 1996 Aug;3(8):789-91. doi: 10.1016/0929-693x(96)82162-2.
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Two-stage approach to total knee arthroplasty using colistin-loaded articulating cement spacer for vancomycin-resistant Pseudomonas aeruginosa infection in an arthritic knee.采用含黏菌素的关节成形水泥间隔器治疗关节炎膝关节中耐万古霉素铜绿假单胞菌感染的全膝关节置换两阶段方法。
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Type-specific cold auto-antibodies as a cause of acquired hemolytic anemia and hemolytic transfusion reactions: biologic test with bovine red cells.特定血型的冷凝集素作为获得性溶血性贫血和溶血性输血反应的病因:用牛红细胞进行生物学检测
Ann Intern Med. 1956 Feb;44(2):221-40. doi: 10.7326/0003-4819-44-2-221.
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[Review of 17 cases of hemolysis caused by auto-antibodies].
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Drug-induced hemolysis: cefotetan-dependent hemolytic anemia mimicking an acute intravascular immune transfusion reaction.药物性溶血:头孢替坦依赖性溶血性贫血酷似急性血管内免疫性输血反应。
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[Auto-immune hemolytic anemia revealed by erythroblastopenia linked to a parvovirus infection].[与细小病毒感染相关的成红细胞减少症所揭示的自身免疫性溶血性贫血]
Arch Fr Pediatr. 1986 Jun-Jul;43(6):409-11.

引用本文的文献

1
A rare occurrence of Vancomycin-induced gastrointestinal hemorrhage without thrombocytopenia: a case report and literature review.万古霉素致胃肠道出血而无血小板减少症的罕见病例报告:病例报告及文献复习。
BMC Infect Dis. 2024 Oct 4;24(1):1105. doi: 10.1186/s12879-024-09949-y.
2
Vancomycin-Induced Hemolytic Anemia.万古霉素诱导的溶血性贫血
Cureus. 2023 May 18;15(5):e39191. doi: 10.7759/cureus.39191. eCollection 2023 May.

本文引用的文献

1
Drug-induced immune hemolytic anemia associated with anti-vancomycin complicated by a paraben antibody.药物诱导的免疫性溶血性贫血,与抗万古霉素相关,并合并对羟基苯甲酸酯抗体。
Transfusion. 2018 Jan;58(1):181-188. doi: 10.1111/trf.14362. Epub 2017 Oct 8.
2
Drug-induced immune hemolytic anemia (Direct Antiglobulin Test positive).药物性免疫性溶血性贫血(直接抗人球蛋白试验阳性)。
Med J Armed Forces India. 2013 Apr;69(2):190-2. doi: 10.1016/j.mjafi.2012.04.017. Epub 2012 Aug 4.
3
Release of gentamicin and vancomycin from preformed spacers in infected total hip arthroplasties: measurement of concentrations and inhibitory activity in patients' drainage fluids and serum.庆大霉素和万古霉素从感染性全髋关节置换术中预制间隔物的释放:患者引流液和血清中浓度及抑制活性的测定
ScientificWorldJournal. 2013 Sep 22;2013:752184. doi: 10.1155/2013/752184. eCollection 2013.
4
One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm.一个中心的经验:与药物性免疫性溶血性贫血相关的血清学和药物——一种新范式。
Transfusion. 2007 Apr;47(4):697-702. doi: 10.1111/j.1537-2995.2007.01173.x.
5
Autoimmune haemolytic anaemia associated with alpha-methyldopa therapy.
Lancet. 1966 Jul 16;2(7455):135-9. doi: 10.1016/s0140-6736(66)92423-8.
6
Penicillin-induced immune hemolytic anemia. Occurrence of massive intravascular hemolysis.青霉素诱发的免疫性溶血性贫血。发生大量血管内溶血。
JAMA. 1975 Aug 4;233(5):432-5.