Department of Physical Therapy, University of Granada, Granada, Spain.
Department of Physical Therapy, Instituto Biosanitario Granada (IBS.Granada), Instituto Mixto Deporte y Salud (iMUDS), University of Granada, Avda. Ilustración 60, 18071, Granada, Granada, Spain.
Support Care Cancer. 2020 Jun;28(6):2891-2898. doi: 10.1007/s00520-019-05173-6. Epub 2019 Nov 21.
Medical treatment for head and neck cancer may induce the presence of inflammation, pain, and dysfunction. The purpose of the current study was to assess the presence of myofascial trigger points (TrPs) and their relationship with widespread pressure hypersensitivity and hyperalgesia in survivors of head and neck cancer (sHNC).
TrPs and pressure-pain thresholds (PPTs) were quantified in different muscles/joints in the head and neck of 30 sHNC (59.45 ± 13.13 years) and 28 age- and sex-matched controls (58.11 ± 12.67 years).
The sHNC had more TrPs in all muscles on the affected side (p < 0.05) than did the healthy controls, and in the temporalis, masseter, and suboccipitalis muscles on the unaffected side (p < 0.05). They also had lower PPTs in all places (p < 0.05) except for the temporalis muscle (p = 0.114) and C5-C6 joint (p = 0.977). The intensity of cervical pain correlated positively with the presence of upper trapezius TrPs.
sHNC suffering cervical and/or temporomandibular joint pain have multiple active TrPs and experience widespread pressure hypersensitivity and hyperalgesia, suggestive of peripheral and central sensitization.
头颈部癌症的治疗可能会引发炎症、疼痛和功能障碍。本研究的目的是评估头颈部癌症幸存者（sHNC）中肌筋膜触发点（TrPs）的存在及其与广泛压痛敏化和痛觉过敏的关系。
在 30 名头颈部癌症幸存者（59.45 ± 13.13 岁）和 28 名年龄和性别匹配的对照组（58.11 ± 12.67 岁）的头颈部不同肌肉/关节中定量测量 TrPs 和压力疼痛阈值（PPTs）。
与健康对照组相比，sHNC 患侧所有肌肉的 TrPs 更多（p < 0.05），且非患侧的颞肌、咬肌和枕下肌的 TrPs 也更多（p < 0.05）。他们在所有部位的 PPTs 都较低（p < 0.05），除了颞肌（p = 0.114）和 C5-C6 关节（p = 0.977）。颈椎疼痛的强度与斜方肌上部 TrPs 的存在呈正相关。
患有颈痛和/或颞下颌关节痛的 sHNC 存在多处活动性 TrPs，并且经历广泛的压痛敏化和痛觉过敏，提示存在外周和中枢敏化。
