Briscoe Jessica, Saumoy Monica, Pickett-Blakely Octavia
Division of Gastroenterology and Hepatology, Temple University Hospital, 3401 N. Broad Street, Philadelphia, PA, 19140, USA.
Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Curr Treat Options Gastroenterol. 2019 Dec;17(4):587-601. doi: 10.1007/s11938-019-00250-5.
Obesity is associated with multiple gastrointestinal and liver diseases such as gastroesophageal reflux disease, Barrett's esophagus, esophageal adenocarcinoma, cholelithiasis, colon polyps, and fatty liver disease. To effectively manage obesity, it is imperative to understand current and emerging therapies and procedures.
Obesity is becoming increasingly prevalent and is associated with a growing monetary health care burden. Cardiac disease, cerebrovascular disease, and diabetes are among the leading causes of preventable and premature death of Americans related to obesity. In addition to behavioral modification (diet and exercise) and bariatric surgery, multiple pharmacotherapies and endoscopic procedures are newly approved and available for the management of obesity. This paper reviews the current literature on the treatments available for the management of obesity including behavior modification, pharmacotherapy, endoscopic weight loss procedures (endobariatrics), and bariatric surgery.
肥胖与多种胃肠道和肝脏疾病相关，如胃食管反流病、巴雷特食管、食管腺癌、胆石症、结肠息肉和脂肪肝疾病。为有效管理肥胖，必须了解当前及新出现的治疗方法和程序。
肥胖正日益普遍，并带来不断增加的医疗费用负担。心脏病、脑血管疾病和糖尿病是与肥胖相关的美国人可预防和过早死亡的主要原因。除行为改变（饮食和运动）及减肥手术外，多种药物疗法和内镜手术新近获批并可用于肥胖管理。本文综述了有关肥胖管理现有治疗方法的当前文献，包括行为改变、药物治疗、内镜减肥手术（内镜减重治疗）和减肥手术。
