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[阑尾切除术后伤口感染。甲硝唑与奥硝唑作为非穿孔性阑尾炎单剂量预防用药的比较]

[Wound infection following appendectomy. Metronidazole vs ornidazole as single-dose prophylaxis in non-perforated appendix].

作者信息

Barth A, Kuhn P, Bertschmann W

机构信息

Chirurgische Klinik, Bürgerspital Solothurn.

出版信息

Schweiz Med Wochenschr. 1988 Oct 1;118(39):1403-5.

PMID:3175579
Abstract

In an open prospective randomized study, the postoperative wound infection rate following removal of an unperforated appendix was evaluated in 187 patients who received either metronidazole (1 g suppositories) or ornidazole (500 mg iv or 500 mg suppositories) in a single dose preoperatively. The overall postoperative infection rate was 2.1%. Metronidazole and ornidazole suppositories are a cheap method of preventing postoperative infection in cases of unperforated appendix.

摘要

在一项开放性前瞻性随机研究中,对187例术前单次接受甲硝唑(1克栓剂)或奥硝唑(500毫克静脉注射或500毫克栓剂)的患者进行了未穿孔阑尾切除术后伤口感染率的评估。总体术后感染率为2.1%。甲硝唑和奥硝唑栓剂是预防未穿孔阑尾病例术后感染的一种廉价方法。

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