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前瞻性多中心波兰应激超声心动图注册研究(PolStress-Echopro)——在临床实践中的作用。

Prospective multicenter Polish Stress Echocardiography Registry (PolStress-Echopro) - the role in clinical practice.

机构信息

Department of Cardiology, School of Health Sciences in Katowice, Medical University of Silesia, Poland.

2nd Department of Cardiology Upper Silesian Medical Centre, Katowice, Poland.

出版信息

Adv Clin Exp Med. 2019 Nov;28(11):1555-1560. doi: 10.17219/acem/100648.

Abstract

BACKGROUND

Stress echocardiography (SE) is becoming an increasingly frequently performed diagnostic examination in Poland. After the published retrospective PolSTRESS Registry, this prospective study is the first one available so far.

OBJECTIVES

The aim of the study was to analyze SE tests, taking into account the clinical characteristics of the patients, indications, applied protocols, and diagnostic and therapeutic decisions.

MATERIAL AND METHODS

Reference cardiological centers in Poland were asked for a 1-month prospective analysis of the data obtained. The study included 189 SE examinations. To evaluate coronary artery disease (CAD) (178 tests), all 17 centers performed dobutamine SE (DSE) (100%), 3 centers (17%) performed pacing, while cycle ergometer and treadmill SE were performed by 1 (5%) and 2 (11%) centers, respectively. In patients with valvular heart disease (VHD) (11 tests), 3 centers (16%) performed SE to evaluate low-flow/low-gradient aortic stenosis (AS), 4 (22%) in asymptomatic AS and 1 (5%) to evaluate mitral regurgitation.

RESULTS

For CAD assessment, a positive result was found in 37 (20%) patients, negative in 109 (61%) and nondiagnostic in 32 (19%). In the CAD group, coronarography was performed in 41 (23%) people. The analysis of the significance of the SE results for decision-making on interventional measures revealed that 30 patients (from the total study population of 189) were referred for the intervention.

CONCLUSIONS

The most commonly used SE is the DSE. Negative test results allowed in almost half of the patients to resign from invasive coronarography. Stress echocardiography should be more frequently used in patients with VHD in the qualification for invasive treatment.

摘要

背景

超声心动图应激试验(SE)在波兰越来越多地被用作诊断检查。在发表了回顾性的 PolSTRESS 注册研究之后,本前瞻性研究是目前为止首例。

目的

本研究旨在分析 SE 检查,同时考虑患者的临床特征、适应证、应用方案以及诊断和治疗决策。

材料与方法

波兰的参考心脏中心被要求进行为期 1 个月的前瞻性数据分析。该研究共纳入 189 例 SE 检查。为评估冠心病(CAD)(178 次检查),所有 17 个中心均进行了多巴酚丁胺 SE(DSE)(100%),3 个中心(17%)进行了起搏,而仅 1 个(5%)和 2 个(11%)中心分别进行了踏车和跑步机 SE。在 11 例瓣膜性心脏病(VHD)患者中,3 个中心(16%)进行 SE 以评估低流量/低梯度主动脉瓣狭窄(AS),4 个中心(22%)在无症状 AS 中进行,1 个中心(5%)用于评估二尖瓣反流。

结果

对于 CAD 的评估,37 例(20%)患者的 SE 结果为阳性,109 例(61%)为阴性,32 例(19%)为非诊断性。在 CAD 组中,有 41 人(23%)进行了冠状动脉造影。对 SE 结果对介入治疗决策的意义进行分析后发现,有 30 名患者(占 189 名总研究人群)被转诊进行介入治疗。

结论

最常使用的 SE 是 DSE。阴性试验结果使近一半的患者能够避免进行有创冠状动脉造影。对于 VHD 患者,在进行有创治疗的资格评估时,应更频繁地使用超声心动图应激试验。

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