Mussard Eugenie, Cesaro Annabelle, Lespessailles Eric, Legrain Brigitte, Berteina-Raboin Sabine, Toumi Hechmi
Laboratory I3MTO, EA 4708, Université d'Orléans, 45067 Orléans Cedex 2, France.
Service de Rhumatologie, Centre Hospitalier Régional d'Orléans 14 Avenue de l'Hôpital, 45100 Orléans, France.
Antioxidants (Basel). 2019 Nov 20;8(12):571. doi: 10.3390/antiox8120571.
Traditionally, has been used as an herbal remedy for lung infection treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for a wide range of biological activities such as antioxidant, anti-inflammatory, and anti-cancer properties. This manuscript is a brief review of the antioxidant mechanisms and the regulation of the Nrf2 (nuclear factor (erythroid-derived 2)-like 2) signaling pathway by andrographolide.
传统上,它一直被用作治疗肺部感染的草药。其叶子含有一种名为穿心莲内酯的二萜类半日花烷,具有广泛的生物活性,如抗氧化、抗炎和抗癌特性。本手稿简要综述了穿心莲内酯的抗氧化机制及其对Nrf2(核因子(红细胞衍生2)样2)信号通路的调控。