Department of Medicine, Nova Southeastern University, Davie, FL, USA; Department of Medicine, University of Miami, Coral Gables, FL, USA.
Med Clin North Am. 2020 Jan;104(1):77-94. doi: 10.1016/j.mcna.2019.09.001.
This article evaluates the role of allergen immunotherapy (AIT) in the treatment of allergic rhinitis (AR). AIT has been shown to be effective in treating AR symptoms with resultant improvements in overall quality of life, comorbid illnesses, and medication requirements. Persistent clinical benefits have been shown years after AIT treatment discontinuation. AIT may prevent the progression of AR to asthma. AIT may more cost-effective than pharmacotherapy. Multiple individual studies and systematic reviews provide strong evidence for the clinical effectiveness of AIT in the treatment of AR. Cost-effectiveness and disease modification of AIT compared with standard drug treatment are additional advantages.
本文评估了变应原免疫治疗（AIT）在治疗过敏性鼻炎（AR）中的作用。AIT 已被证明可有效治疗 AR 症状，从而提高整体生活质量、合并症和药物需求。在 AIT 治疗停止多年后仍显示出持续的临床获益。AIT 可能预防 AR 向哮喘发展。AIT 可能比药物治疗更具成本效益。多项个体研究和系统评价为 AIT 在治疗 AR 中的临床疗效提供了强有力的证据。与标准药物治疗相比，AIT 的成本效益和疾病改善是其额外的优势。
