• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

膈肌起搏器植入手术的麻醉管理。我们在古特曼研究所的经验。

Anesthetic management of the diaphragmatic pacemaker placement surgery. Our experience in the Institut Guttmann.

作者信息

Alegret N, Serra P, Pessas J P, Curià X, Vidal J, Valero R

机构信息

Servicio de Anestesiología y Reanimación, Institut Guttmann, Badalona, Barcelona, España.

Servicio de Anestesiología y Reanimación, Institut Guttmann, Badalona, Barcelona, España.

出版信息

Rev Esp Anestesiol Reanim (Engl Ed). 2019 Dec;66(10):497-505. doi: 10.1016/j.redar.2019.10.005. Epub 2019 Nov 20.

DOI:10.1016/j.redar.2019.10.005
PMID:31759615
Abstract

BACKGROUND

The diaphragm pacemaker (DP) has proven its utility in replacing mechanical ventilation in patients with chronic spinal cord injury (SCI) and amyotrophic lateral sclerosis (ALS). The DP improves patient quality of life and reduces morbidity and mortality and their associated health care costs. The anesthetic management of these patients and the particularities of the surgical procedure are challenging. The aim of our study is to analyze anesthetic management and intraoperative complications in patients undergoing DP placement in our hospital.

METHODS

We performed a chart review of patients treated between December 2007 and July 2017, recording the patients' preoperative status, anesthetic management and intraoperative complications.

RESULTS

The study included 16 patients (5 pediatric) undergoing DP implantation for chronic SCI (63%), ALS (25%) and other neurologic conditions (12%). Abdominal laparoscopy was performed under general anesthesia, with intravenous (87%) or inhalational (13%) induction and maintenance using total intravenous (50%) or balanced (50%) anesthesia. Rocuronium was administered in one case to permit airway management. Complications included: hypotension (50%), difficulties in mechanical ventilation during laparoscopy (31%), pneumothorax (12.5%) and autonomic dysreflexia (6%).

CONCLUSIONS

DP placement under general anesthesia is a safe intervention in both adult and pediatric patients. Complications derived from both the underlying disease and the surgical technique may appear, and must be rapidly identified and treated to obtain a satisfactory surgical outcome.

摘要

背景

膈神经起搏器(DP)已在慢性脊髓损伤(SCI)和肌萎缩侧索硬化症(ALS)患者中证明其在替代机械通气方面的效用。DP可改善患者生活质量,降低发病率和死亡率及其相关的医疗保健成本。这些患者的麻醉管理以及手术过程的特殊性具有挑战性。我们研究的目的是分析在我院接受DP植入患者的麻醉管理和术中并发症。

方法

我们对2007年12月至2017年7月期间接受治疗的患者进行了病历审查,记录患者的术前状况、麻醉管理和术中并发症。

结果

该研究包括16例患者(5例儿科患者),因慢性SCI(63%)、ALS(25%)和其他神经系统疾病(12%)接受DP植入。在全身麻醉下进行腹部腹腔镜检查,采用静脉诱导(87%)或吸入诱导(13%),并使用全静脉麻醉(50%)或平衡麻醉(50%)进行维持。1例患者使用罗库溴铵以利于气道管理。并发症包括:低血压(50%)、腹腔镜检查期间机械通气困难(31%)、气胸(12.5%)和自主神经反射异常(6%)。

结论

全身麻醉下的DP植入对成人和儿科患者都是一种安全的干预措施。可能会出现由基础疾病和手术技术引起的并发症,必须迅速识别并治疗,以获得满意的手术结果。

相似文献

1
Anesthetic management of the diaphragmatic pacemaker placement surgery. Our experience in the Institut Guttmann.膈肌起搏器植入手术的麻醉管理。我们在古特曼研究所的经验。
Rev Esp Anestesiol Reanim (Engl Ed). 2019 Dec;66(10):497-505. doi: 10.1016/j.redar.2019.10.005. Epub 2019 Nov 20.
2
Perioperative anesthetic management of children with congenital central hypoventilation syndrome and rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation undergoing thoracoscopic phrenic nerve-diaphragm pacemaker implantation.先天性中枢性低通气综合征合并快速进展性肥胖伴下丘脑功能障碍、低通气及自主神经失调的患儿,在接受胸腔镜膈神经-膈肌起搏器植入术时的围手术期麻醉管理。
Paediatr Anaesth. 2018 Nov;28(11):963-973. doi: 10.1111/pan.13475. Epub 2018 Sep 24.
3
Diaphragmatic pacing stimulation in spinal cord injury: anesthetic and perioperative management.脊髓损伤中的膈肌起搏刺激:麻醉和围手术期管理。
Clinics (Sao Paulo). 2012 Nov;67(11):1265-9. doi: 10.6061/clinics/2012(11)07.
4
Complete worldwide operative experience in laparoscopic diaphragm pacing: results and differences in spinal cord injured patients and amyotrophic lateral sclerosis patients.腹腔镜膈神经起搏的全球手术经验:脊髓损伤患者和肌萎缩侧索硬化症患者的结果及差异
Surg Endosc. 2009 Jul;23(7):1433-40. doi: 10.1007/s00464-008-0223-3. Epub 2008 Dec 6.
5
Video-assisted thoracoscopic implantation of a diaphragmatic pacemaker in a child with tetraplegia: indications, technique, and results.电视辅助胸腔镜下为一名四肢瘫痪儿童植入膈肌起搏器:适应症、技术及结果
J Bras Pneumol. 2015 Jan-Feb;41(1):90-4. doi: 10.1590/S1806-37132015000100011.
6
[Diaphragmatic pacemaker dysfunction and utility of diaphragmatic ultrasonography].[膈肌起搏器功能障碍与膈肌超声检查的效用]
Rehabilitacion (Madr). 2019 Apr-Jun;53(2):116-120. doi: 10.1016/j.rh.2019.01.002. Epub 2019 Mar 29.
7
Multicenter review of diaphragm pacing in spinal cord injury: successful not only in weaning from ventilators but also in bridging to independent respiration.脊髓损伤中膈神经刺激的多中心回顾:不仅有助于脱机,而且有助于向自主呼吸过渡,效果良好。
J Trauma Acute Care Surg. 2014 Feb;76(2):303-9; discussion 309-10. doi: 10.1097/TA.0000000000000112.
8
Diaphragmatic reinnervation in ventilator-dependent patients with cervical spinal cord injury and concomitant phrenic nerve lesions using simultaneous nerve transfers and implantable neurostimulators.在依赖呼吸机的颈脊髓损伤并伴有膈神经损伤患者中,使用同步神经移植和植入式神经刺激器进行膈神经再支配。
J Reconstr Microsurg. 2015 Jun;31(5):391-5. doi: 10.1055/s-0035-1549159. Epub 2015 Apr 13.
9
The impact of a specialized spinal cord injury center as compared with non-specialized centers on the acute respiratory management of patients with complete tetraplegia: an observational study.专门的脊髓损伤中心与非专门中心相比,对完全性四肢瘫痪患者急性呼吸管理的影响:一项观察性研究。
Spinal Cord. 2018 Feb;56(2):142-150. doi: 10.1038/s41393-017-0003-9. Epub 2017 Nov 15.
10
Early diaphragm pacing in patients with amyotrophic lateral sclerosis (RespiStimALS): a randomised controlled triple-blind trial.肌萎缩侧索硬化症患者的早期膈肌起搏(RespiStimALS):一项随机对照三盲试验。
Lancet Neurol. 2016 Nov;15(12):1217-1227. doi: 10.1016/S1474-4422(16)30233-2. Epub 2016 Oct 11.

引用本文的文献

1
Paced breathing and respiratory movement responses evoked by bidirectional constant current stimulation in anesthetized rabbits.麻醉兔双向恒流刺激诱发的定频呼吸和呼吸运动反应
Front Bioeng Biotechnol. 2023 Jan 12;10:1109892. doi: 10.3389/fbioe.2022.1109892. eCollection 2022.