Sarpong Nana O, Sonnenfeld Julian J, LiArno Sally, Rajaravivarma Raga, Donde Sonia, Sneddon Emily, Kaverina Tatyana, Cooper H John, Shah Roshan P, Geller Jeffrey A
Center for Hip and Knee Replacement, Department of Orthopedic Surgery, Columbia University Irving Medical Center, 622 West 168th Street PH 1138, New York, NY 10032, United States of America.
Center for Hip and Knee Replacement, Department of Orthopedic Surgery, Columbia University Irving Medical Center, 622 West 168th Street PH 1138, New York, NY 10032, United States of America.
Knee. 2020 Jan;27(1):151-156. doi: 10.1016/j.knee.2019.10.023. Epub 2019 Nov 21.
Total knee arthroplasty (TKA) design continues to be refined. As part of the pre-clinical design process, kinematic evaluation under ideal circumstances must be simulated. Previously, this was accomplished mechanically through the use of elastomeric bumpers and human cadaver models, which can be costly and time-intensive. With improved technology, a six-axis joint simulator now allows for virtual ligament reconstruction. The aim of this study was to create and evaluate a virtual posterior cruciate ligament (PCL) model to simulate native knee kinematics for component testing in TKA.
Three human cadaveric knee specimens were utilized, each mounted in a six-axis joint simulator and the femoral and tibial ligament insertion points digitized. Ligament stiffness and kinematics were first tested with the intact knee, followed by retesting after PCL transection. Knee kinematic testing was then repeated, and the virtual PCL was reconstructed until it approximated that of the intact knee by achieving less than 10% random mean square (RMS) error.
A virtual three-bundle PCL was created. The RMS error in anterior-posterior motion between the virtually reconstructed PCL and the intact knee ranged from six to eight percent for simulated stair climbing in the three knee specimens tested, all within our target goal of less than 10%.
This study indicated that a virtually reconstructed three-bundle PCL with a joint simulator can replicate knee kinematics. Such an approach is valuable to obtain clinically relevant kinematics when testing cruciate-retaining total knee arthroplasty under force control.
全膝关节置换术(TKA)的设计仍在不断完善。作为临床前设计过程的一部分,必须模拟理想情况下的运动学评估。以前,这是通过使用弹性缓冲器和人体尸体模型以机械方式完成的,成本高且耗时。随着技术的进步,六轴关节模拟器现在可以进行虚拟韧带重建。本研究的目的是创建并评估一个虚拟后交叉韧带(PCL)模型,以模拟天然膝关节运动学,用于TKA组件测试。
使用三个人体尸体膝关节标本,每个标本安装在六轴关节模拟器中,并对股骨和胫骨韧带插入点进行数字化处理。首先对完整膝关节进行韧带刚度和运动学测试,然后在PCL横断后重新测试。然后重复膝关节运动学测试,并重建虚拟PCL,直到通过实现小于10%的随机均方(RMS)误差来近似完整膝关节的运动学。
创建了一个虚拟三束PCL。在测试的三个膝关节标本中,模拟上楼梯时,虚拟重建的PCL与完整膝关节之间前后运动的RMS误差在6%至8%之间,均在我们设定的小于10%的目标范围内。
本研究表明,使用关节模拟器虚拟重建的三束PCL可以复制膝关节运动学。在力控制下测试保留交叉韧带的全膝关节置换术时,这种方法对于获得临床相关的运动学非常有价值。