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什么是癌症?

What Is Cancer?

作者信息

Hausman Daniel M

出版信息

Perspect Biol Med. 2019;62(4):778-784. doi: 10.1353/pbm.2019.0046.

Abstract

This essay focuses on themes in Explaining Cancer: Finding Order in Disorder (2018) by Anya Plutynski, a monograph that has important things to say about both the peculiarities of cancers and our theories about them. Cancer's agents of destruction are human cells that have been recruited and to some extent transformed into pathological organisms or the building blocks of tumors. Cancers both undermine and exploit mechanisms of multicellular organization, and understanding them gives rise to difficult philosophical problems. In addition to sketching Plutynski's discussion of these problems, this essay defends Christopher Boorse's account of disease from Plutynski's criticisms, and it expresses some qualms about her treatment of scientific explanation.

摘要

本文聚焦于安雅·普鲁蒂恩斯基所著的《解释癌症:在无序中寻找秩序》(2018年)中的主题,这是一本关于癌症的特性以及我们对其理论的专著,书中有很多重要观点。癌症的破坏因子是人体细胞,这些细胞被招募并在一定程度上转化为病理有机体或肿瘤的组成部分。癌症既破坏又利用多细胞组织的机制,而理解这些会引发棘手的哲学问题。除了概述普鲁蒂恩斯基对这些问题的讨论,本文还回应了普鲁蒂恩斯基对克里斯托弗·博尔泽疾病理论的批评,并对她对科学解释的论述表达了一些疑虑。

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