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[无明显白质脑病的淀粉样β相关血管炎]

[Amyloid β related angitis without marked leukoencephalopathy].

作者信息

Taniguchi Yoko, Kitamura Taro, Inoue Hiroyasu, Miura Toshiyasu, Yamada Kentaro

机构信息

Department of Neurology, Nagoya City East Medical Center.

出版信息

Rinsho Shinkeigaku. 2019 Dec 25;59(12):814-817. doi: 10.5692/clinicalneurol.cn-001278. Epub 2019 Nov 23.

Abstract

An 86-year-old woman was admitted to our hospital with headache and acute detarioration of consciousness. Cerebral microbleeds (CMBs) dominated the occipital lobe on the head MRI, revealing white matter lesions. It was accompanied by gadolinium (Gd) imaging effect in the leptomeninges and some CMBs. She was clinically diagnosed with amyloid β-related vasculitis and a good outcome was obtained with steroid therapy. Even when symptoms re-exacerbated, exacerbation of the contrast effect of CMBs was observed, but no white matter lesions appeared, and leptomeningeal enhancement did not change remarkably throughout the entire course.

摘要

一名86岁女性因头痛和意识急性恶化入住我院。头部MRI显示脑微出血(CMB)主要位于枕叶,伴有白质病变。软脑膜和部分CMB有钆(Gd)成像效应。临床诊断为淀粉样β相关血管炎,经类固醇治疗后预后良好。即使症状再次加重,CMB的对比效应也会加重,但未出现白质病变,整个病程中软脑膜强化无明显变化。

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