Maung R, Kelly J K, Grace D A
Department of Pathology, Foothills Hospital, Calgary, Alberta, Canada.
Urology. 1988 Oct;32(4):361-3. doi: 10.1016/0090-4295(88)90246-4.
We report a case of intestinal metaplasia and dysplasia (villous adenoma) of the prostatic urethra secondary to stricture of the prostatic portion of the urethra and chronic inflammation. This sequence of events has previously been recognized in the urothelium of the bladder as a precursor of adenocarcinoma of intestinal type. Premalignant dysplasia of glandular type is rare in the urethra, as is adenocarcinoma, and this case suggests that the pathway to some adenocarcinomas of the urethra may be through intestinal metaplasia and dysplasia similar to the process recognized in the stomach, nose, and urinary bladder.
我们报告一例继发于尿道前列腺部狭窄和慢性炎症的前列腺尿道肠化生及发育异常（绒毛状腺瘤）病例。此前在膀胱尿路上皮中已认识到这一系列事件是肠型腺癌的先兆。腺型癌前发育异常在尿道中罕见，腺癌亦如此，该病例提示，某些尿道腺癌的发病途径可能是通过肠化生和发育异常，类似于在胃、鼻和膀胱中所认识到的过程。
