Bashir Shahid, Baradi Raidah, Al-Ghamdi Fouad
Neuroscience Center, King Fahd Specialist Hospital Dammam, Dammam, Saudi Arabia.
Acta Inform Med. 2019 Sep;27(3):171-176. doi: 10.5455/aim.2019.27.171-176.
Voxel-based morphometry (VBM) is a neuroimaging analysis technique that allows investigation of focal differences in brain anatomy, using the statistical approach of statistical parametric mapping. Gender changes are probably expressed in the human brain in the form of functional and anatomical organization.
Our aim was to study gender differences and anatomical abnormalities in epilepsy patients (EP) by voxel-based morphometry (VBM) methods.
Cortical thickness analysis of whole brain was performed in 28 patients with EP and 30 controls for gender and hemispheric differences.
Cortical thickness abnormalities were more widespread in left side of the brain in EP; while in female changes were mostly seen in temporal areas, frontal regions were more affected in male.
Our study confirmed that gender and laterality are important factors determining the brain damage in EP.
基于体素的形态测量学（VBM）是一种神经影像学分析技术，它使用统计参数映射的统计方法来研究脑解剖结构中的局灶性差异。性别变化可能以功能和解剖结构组织的形式在人类大脑中表现出来。
我们的目的是通过基于体素的形态测量学（VBM）方法研究癫痫患者（EP）的性别差异和解剖学异常。
对28例癫痫患者和30名对照者进行全脑皮质厚度分析，以研究性别和半球差异。
癫痫患者大脑左侧的皮质厚度异常更为普遍；女性的变化主要出现在颞叶区域，而男性额叶受影响更大。
我们的研究证实，性别和脑半球优势是决定癫痫患者脑损伤的重要因素。
