Dzananovic Amra, Begic Amela, Pokrajac Danka
Department of Paediatric Radiology, Clinic for Radiology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Clinic for Nuclear Medicine and Endocrinology, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Acta Inform Med. 2019 Sep;27(3):181-185. doi: 10.5455/aim.2019.27.181-185.
Congenital hydronephrosis (CH) is a condition with dilated renal pelvis with or without dilation of renal calyces.
To examine the role of magnetic resonance urography in the detection of congenital hydronephrosis in comparison to dynamic renal scintigraphy (DRS).
Resarch included 58 (n=58) patients with diagnosis of congenital unilateral or bilateral dilatation of kidney duct system. Each patient had a one-time or multiple hospitalization at the Nephrology Department of the Pediatric Clinic, with performed: ultrasound which confirmed CH, voiding cystourethrography / voiding urosonography was confirmed based on which the vesicoureteral reflux (VUR) was established / excluded, dynamic renal scintigraphy and magnetic urography (analysis was made by CHOP-fMRU software) on the basis of which the uterine anatomy and the relative renal function were evaluated.
Male patients were represented in 40 cases (69%). The average age was 4.4 ± 4.3 years with the youngest patient at the age of 2 months, and the oldest was 17 years old. According to diagnostic entities, the most common diagnosis was ureteropelvic junction (UPJ) obstruction in over half of cases (30 or 51.7%), followed by subjects with ureterovesical junction (UVJ) obstruction (11 or 19%), VUR was recorded in 9 (15.5%) cases, and pyelon fissus in 7 (12.1%), and one case (1.7%) was recorded with bilateral megaureter. Comparison of the value of the renal function obtained with DRS and CHOP-fMRU methods shows that there were no statistically significant differences between two methods. In the case of right kidney, the mean DRS value was 53.4 ± 18.4% (range 13-100%), while CHOP-fMRU was 51.8 ± 22.4 (range 0-96.7%). In the case of left kidney, the average value according to the DRS method was 46.9 ± 18.9% (range 0-87%) and according to CHOP-fMRU 47.6 ± 21.5% (range 8.3-100%). The correlation coefficients of both right and left kidneys show a highly statistically significant correlation between these two methods.
Magnetic resonance urography in the pediatric population in CH based on results should be an integral part of the management of these patients, especially in congenital obstructive uropathy, in complex and associated congenital anomalies, as it provides morphological and functional data on the state of the kidneys and urinary tract.
先天性肾积水(CH)是一种肾盂扩张的病症,可伴有或不伴有肾盏扩张。
与动态肾闪烁显像(DRS)相比,研究磁共振尿路造影在先天性肾积水检测中的作用。
研究纳入58例诊断为先天性单侧或双侧肾导管系统扩张的患者。每位患者均在儿科诊所肾病科住院一次或多次,接受了以下检查:超声检查确诊为CH,排尿性膀胱尿道造影/排尿性超声检查确诊后确定有无膀胱输尿管反流(VUR),动态肾闪烁显像和磁共振尿路造影(采用CHOP-fMRU软件进行分析),在此基础上评估肾盂解剖结构和相对肾功能。
男性患者40例(69%)。平均年龄为4.4±4.3岁,最年轻的患者为2个月,最年长的为17岁。根据诊断类型,最常见的诊断是输尿管肾盂连接部(UPJ)梗阻,超过半数病例(30例,占51.7%),其次是输尿管膀胱连接部(UVJ)梗阻患者(11例,占19%),9例(15.5%)记录有VUR,7例(12.1%)有肾盂裂,1例(1.7%)为双侧巨输尿管。比较DRS和CHOP-fMRU方法获得的肾功能值,结果显示两种方法之间无统计学显著差异。右侧肾脏方面,DRS的平均数值为53.4±18.4%(范围13 - 100%),而CHOP-fMRU为51.8±22.4(范围0 - 96.7%)。左侧肾脏方面,DRS方法的平均值为46.9±18.9%(范围0 - 87%),CHOP-fMRU为47.6±21.5%(范围8.3 - 100%)。左右两侧肾脏的相关系数均显示这两种方法之间存在高度统计学显著相关性。
基于研究结果,磁共振尿路造影在儿科先天性肾积水患者的治疗中应成为不可或缺的一部分,尤其是在先天性梗阻性肾病、复杂及相关先天性畸形的情况下,因为它能提供肾脏和尿路状况的形态学和功能数据。