Marzouk Sameh, Frikha Olfa, Guermazi Mouna, Snoussi Mouna, Jallouli Moez, Bahloul Zouhir
Department of Internal Medicine, Hedi Chaker Hospital, Sfax, Tunisia.
Pan Afr Med J. 2019 Sep 9;34:17. doi: 10.11604/pamj.2019.34.17.17901. eCollection 2019.
Adult-onset Still's disease (AOSD) has been recognized as a cause of fevers of unknown origin. Malignancies are the most important differential diagnoses of AOSD which has been rarely reported in association with cancer. The present paper undertakes the study of a 69-year-old Tunisian woman with AOSD according to the diagnostic criteria of Yamaguchi. She was treated by prednisone, then associated with methotrexate. 18 months later, she developed a squamous cell carcinoma treated with chemotherapy and radiotherapy.
成人斯蒂尔病(AOSD)已被确认为不明原因发热的一个病因。恶性肿瘤是AOSD最重要的鉴别诊断,AOSD与癌症相关的情况鲜有报道。本文依据山口的诊断标准,对一名69岁的突尼斯AOSD女性患者展开研究。她最初接受泼尼松治疗,之后联合甲氨蝶呤治疗。18个月后,她患上了鳞状细胞癌,并接受了化疗和放疗。