Brunner H
I. Interen Abteilung mit Gastroenterologie, Krankenhauses der Elisabethinen, Linz.
Wien Med Wochenschr. 1988 Jun 30;138(11-12):261-3.
The poor results of nonsurgical cancer therapy in locally recurring colorectal carcinoma and its metastases urge for an early diagnosis of these complications. Serial CEA-levels are the most promising tool to detect even preclinical tumour-growth. Because the incidence of tumor recurrence or metastases is highest in the first and second year after surgery the follow-up of the patients should be as close as possible during this time.
局部复发性结直肠癌及其转移灶的非手术癌症治疗效果不佳，这就迫切需要对这些并发症进行早期诊断。连续检测癌胚抗原（CEA）水平是检测甚至是临床前肿瘤生长最有前景的工具。由于肿瘤复发或转移的发生率在术后第一年和第二年最高，因此在此期间应尽可能密切地对患者进行随访。
