Division of Urologic Surgery, University of Nebraska Medical Center, Omaha, NE.
Section of Pediatric Urology, University of Nebraska Medical Center and Children's Hospital & Medical Center, Omaha, NE.
Urology. 2020 Mar;137:161-163. doi: 10.1016/j.urology.2019.11.011. Epub 2019 Nov 23.
Rhabdomyosarcoma (RMS) is a rare malignancy that can develop in nearly any soft-tissue of the body. Location of the primary tumor affects treatment strategy and prognosis, and RMS of the perineal areas can be especially difficult to treat successfully. RMS is treated systemically with chemotherapy. Local control options include surgical excision, radiation treatment, or a combination of the 2. Treating RMS with radiation treatment can be challenging due to the absence of standardized dosage protocols, along with the presence of conflicting recommendations in the literature. Each case of perineal RMS may benefit from a more individualized treatment plan.
横纹肌肉瘤（RMS）是一种罕见的恶性肿瘤，几乎可以在身体的任何软组织中发展。原发肿瘤的位置影响治疗策略和预后，而会阴部的 RMS 尤其难以成功治疗。RMS 通过化疗进行全身性治疗。局部控制选择包括手术切除、放射治疗或两者的组合。由于缺乏标准化剂量方案，以及文献中存在相互矛盾的建议，用放射治疗 RMS 具有挑战性。每个会阴部 RMS 病例可能都受益于更个体化的治疗计划。
